Sökning: "airway inflammation"

Visar resultat 21 - 25 av 187 avhandlingar innehållade orden airway inflammation.

  1. 21. Epithelial signatures in respiratory disease

    Författare :Elisabeth Ax; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; inflammation; gene expression; extracellular vesicles; miRNA;

    Sammanfattning : The epithelium of the human airways protects us against harm and helps maintain immune homeostasis. In respiratory diseases such as asthma and COPD, the functions of the epithelium are altered and can cause or contribute to disease progression. LÄS MER

  3. 22. T cells in chronic obstructive pulmonary disease

    Författare :Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER

  4. 23. On airway host defence during allergic inflammation

    Författare :Anele Gela; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

    Sammanfattning : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. LÄS MER

  5. 24. T cells and smoke-induced airway inflammation

    Författare :Mikael Mikko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD) is an inflammatory disease primarily caused by longterm cigarette smoking. The disease is characterized by both tissue remodelling and an accumulation of inflammatory cells including macrophages, neutrophils and T cells, in the lung. LÄS MER

  7. 25. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

    Författare :Yaping Zhang; Klinisk och experimentell allergiforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

    Sammanfattning : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. LÄS MER