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Visar resultat 1 - 5 av 187 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Allergic airway disease : studies on diesel exhaust exposures, oxylipins and antioxidants

    Författare :Nirina Larsson; Annelie Behndig; Leif Bjermer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; allergic rhinits; diesel exhaust; airway inflammation; oxylipins; metabolomics; antioxidants; SVCT2; bronchoscopy; lungmedicin; Lung Medicine;

    Sammanfattning : Allergic airway disease, i.e. allergic rhinitis (AR) and asthma, is a common health problem. The prevalence is increasing in most countries of the world. LÄS MER

  2. 2. Ozone and diesel exhaust : airway signaling, inflammation and pollutant interactions

    Författare :Jenny Bosson; Anders Blomberg; Thomas Sandström; Ellinor Ädelroth; John Balmes; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; ozone; diesel exhaust; airway inflammation; asthma; immunohistochemistry; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : It is well established that air pollution has detrimental effects on both human health as well as the environment. Exposure to ozone and particulate matter pollution, is associated with an increase in cardiopulmonary mortality and morbidity. Asthmatics, elderly and children have been indicated as especially sensitive groups. LÄS MER

  3. 3. Lung mechanics and airway inflammation in murine models of asthma

    Författare :Sofia Jonasson; Josephine Hjoberg; Hedenstierna Göran; Carl Persson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; airway inflammation; murine models; lung mechanics; forced oscillation technique; airway reactivity; deep inhalations; oxidative stress; nitric oxide; glucocorticoids.; Clinical physiology; Klinisk fysiologi; klinisk fysiologi; Clinical Physiology;

    Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterized by eosinophilic inflammation and increased airway reactivity. In the studies presented in this thesis, lung mechanics and measurements of airway reactivity were assessed in anaesthetized tracheostomized mice by using an animal ventilator (flexiVent®). LÄS MER

  4. 4. Nitric oxide within the concept of united airway disease : Exhaled and nasal nitric oxide in cystic fibrosis, asthma and upper airway inflammatory diseases

    Författare :Christina Krantz; Andrei Malinovschi; Kjell Alving; Celeste Porsbjerg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nitric oxide; nasal NO; exhaled NO; asthma; cystic fibrosis; airway inflammation; upper airway inflammatory disorders; united airway disease; IgE sensitisation; Lungmedicin; Lung Medicine; Pediatrik; Pediatrics;

    Sammanfattning : Background: Within the concept of united airway disease, it is postulated that inflammatory disorders in the upper and lower airways are interrelated and influence each other. Fractional exhaled nitric oxide (FeNO) is an established biomarker of type-2 inflammation in the lower airways and is elevated in patients with asthma. LÄS MER

  5. 5. Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents

    Författare :Louise Fornander; Mats Lindahl; Bijar Ghafouri; Pål Graff; Magnus Svartengren; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : People are, in their daily lives, exposed to a number of airborne foreign compounds that do not normally affect the body. However, depending on the nature of these compounds, dose and duration of exposure, various airway symptoms may arise. LÄS MER