Sökning: "airway disease"
Visar resultat 6 - 10 av 202 avhandlingar innehållade orden airway disease.
6. Epithelial signatures in respiratory disease
Sammanfattning : The epithelium of the human airways protects us against harm and helps maintain immune homeostasis. In respiratory diseases such as asthma and COPD, the functions of the epithelium are altered and can cause or contribute to disease progression. LÄS MER
7. Lung mechanics and airway inflammation in murine models of asthma
Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterized by eosinophilic inflammation and increased airway reactivity. In the studies presented in this thesis, lung mechanics and measurements of airway reactivity were assessed in anaesthetized tracheostomized mice by using an animal ventilator (flexiVent®). LÄS MER
8. Airway effects of diesel exhaust in healthy and asthmatic subjects
Sammanfattning : Several epidemiological studies have revealed an association between particulate matter (PM) pollution and various health effects. Importantly, there is evidence to suggest that individuals with pre-existing respiratory disease, such as asthma, are more sensitive to elevated ground levels of particulate matter as compared to healthy subjects. LÄS MER
9. Chronic obstructive pulmonary disease : clinical phenotyping, mortality and causes of death
Sammanfattning : Background: Chronic obstructive pulmonary disease (COPD) is common. The estimated prevalence is about 10% among adults, but varies largely dependent on the major risk factors age and smoking. Under-diagnosis of COPD is substantial and is related to disease severity. LÄS MER
10. New Mediators and Novel Mechanisms in Allergic Airway Inflammation
Sammanfattning : Hyperresponsiveness and inflammation are major pathophysiological features of both allergic rhinitis and asthma. The mechanisms behind these are not fully understood. LÄS MER