Sökning: "adverse effects"

Visar resultat 11 - 15 av 1040 avhandlingar innehållade orden adverse effects.

1. 11. Cardiovascular effects of diesel exhaust : mechanistic and interventional studies

   Författare :Magnus Lundbäck; Anders Blomberg; Benoit Nemery; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; diesel exhaust; nitrogen dioxide; endothelin-1; cardiovascular effects; exhaust particle trap; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

   Sammanfattning : Background: Air pollution is associated with negative health effects. Exposure to combustion-derived particulate matter (PM) air pollution has been related to increased incidence of cardiovascular and respiratory morbidity and mortality, specifically in susceptible populations. Ambient particles, with a diameter of less than 2. LÄS MER

3. 12. Medication adherence, side effects and patient-physician interaction in hypertension

   Författare :Staffan Svensson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patient compliance; guideline adherence; hypertension; adverse effects; communication; negotiating;

   Sammanfattning : Hypertension is an important risk factor for cardiovascular disease, the incidence of which it is possible to reduce by prophylactic treatment with antihypertensive drugs. In clinical practice, however, only a minority of patients reach target blood pressure levels. LÄS MER

4. 13. Congestion Charging in Urban Networks : Modelling Issues and Simulated Effects

   Författare :Ida Kristoffersson; Leonid Engelson; Otto Anker Nielsen; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Transport Modelling; Congestion Charging; Departure Time Choice; Dynamic Traffic Simulation; Welfare Effects; Equity;

   Sammanfattning : One of the major challenges cities face today, in their development towards sustainable urban areas, is the need for an efficient and environmentally friendly transport system. This transport system should manage to tie together the city without strong adverse impact on urban environment, air-quality and climate change. LÄS MER

5. 14. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?

   Författare :Assel Sarsenbayeva; Jan Eriksson; Mikael Rydén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human adipose tissue; metabolic adverse effects; SGAs; statins; glucocorticoids; glucose uptake; lipolysis; myofibroblasts; fibrosis; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

   Sammanfattning : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. LÄS MER

7. 15. Pharmacogenetics and Antipsychotic Treatment in Schizophrenia with Special Focus on Adverse Drug Reactions

   Författare :Arzu Gunes; Marja-Liisa Dahl; Maria Gabriella Scordo; Kristina I. Melkersson; Jürgen Brockmöller; Uppsala universitet; []
   Nyckelord :Medicine; Pharmacogenetics; schizophrenia; antipsychotic treatment; adverse effects; clinical outcome; Medicin;

   Sammanfattning : Genetically determined differences in drug metabolism and disposition and drug targets play a pivotal role in the interindividual variability in the clinical outcome of antipsychotic treatment. The aim of this thesis was to study the impact of polymorphisms in genes involved in the pharmacokinetics and pharmacodynamics of antipsychotics, with special focus on their extrapyramidal and metabolic adverse effects. LÄS MER