Sökning: "adverse drug reaction"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden adverse drug reaction.

1. 6. Pharmacovigilance : spontaneous reporting in health care

   Författare :Elisabet Ekman; Göran Petersson; Susanna Wallerstedt; Linnéuniversitetet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacovigilance; adverse drug reaction; spontaneous reporting; nurses; physicians; attitudes; torsades de pointes; erectile dysfunction; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Pharmacovigilance in healthcare is essential for safe drug treatment. Spontaneous reporting is the most common source of information in the context of implementing label changes and taking a drug off the market. However, underreporting is found to be very prevalent. LÄS MER

3. 7. A Pill for the Ill? : Depression, Medicalization and Public Health

   Författare :Andreas Vilhelmsson; Socialmedicin och global hälsa; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Pharmaceuticalization; Medicalization; Adverse drug reaction; Antidepressants; Consumer reporting; Depression; Medical encounter; Mental health; Public health;

   Sammanfattning : Mental disorders, especially depression, have been increasingly described as a growing burden to global public health. Critics argue, however, that the use of mental health surveys, underlying these descriptions, tends to overestimate the prevalence of mental disorders by not distinguishing everyday experiences of distress from pathological conditions. LÄS MER

4. 8. 5-HT2A : a serotonin receptor with a possible role in joint diseases

   Författare :Anders Kling; Solbritt Rantapää-Dahlqvist; Carl-Olav Stiller; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 5-HT2A serotonin receptor; serotonin; rheumatoid arthritis; adverse drug reaction; HTR2A; glucocorticoids; klinisk farmakologi; Clinical Pharmacology;

   Sammanfattning : BackgroundSerotonin (5-HT), an amino acid derivative and neurotransmitter, has for long been studied in relation to inflammation. It is an endogenous ligand for several different types of serotonin receptors. The serotonin receptor 5-HT2A has been reported to have a role in the pathophysiology of arthritis in animal experiment models. LÄS MER

5. 9. A systematic approach to improving pharmacotherapy in the elderly

   Författare :Anna Bergkvist; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medication reconciliation; medication report; medication errors; LIMM; inpatients; hospital discharge; elderly; Clinical pharmacy; drug related problem; medication review;

   Sammanfattning : The aim of this thesis was to investigate whether a structured and systematic approach on improving pharmacotherapy in the elderly (the LIMM-model) would lead to a more appropriate and accurate drug use in the elderly. The elderly use many drugs and are more prone to suffer from adverse drug reaction. LÄS MER

7. 10. Cytochrome P450 pharmacogenetics : implications for anticancer and warfarin therapy

   Författare :Mi-Young Lee; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : There is a pronounced interindividual variability in the drug disposition, response and toxicity. Pharmacogenetics aims at identifying genetic biomarkers that could help to increase the drug efficacy, reduce adverse drug reactions and contribute to the development of personalized medicine. LÄS MER