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Visar resultat 1 - 5 av 36 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

    Författare :Henrik Borg; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; secreting systems; Endocrinology; seropositive; seronegative; slowly-progressive; Type 2; Type 1; classification; IA-2A; IA-2; GADA; GAD; ICA; islet antibodies; C-peptide; beta cell function; diabetes mellitus; adult-onset; sekretion; diabetologi;

    Sammanfattning : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. LÄS MER

  3. 2. The female offender : patterning of antisocial and criminal behaviour over the life-course

    Författare :Frida Andersson; Malmö högskola; []
    Nyckelord :criminal career; female offending; trajectories; sex differences; adult onset; chronics; life-course;

    Sammanfattning : The studies included in the thesis illustrate the patterning of female offending over the life course. The overarching aim is to contribute to a better understanding of the female offender and of the heterogeneity in female criminal offending trajectories over the life course, and also of factors that differentiate between these trajectories. LÄS MER

  4. 3. Radiological studies of LMNB1-related autosomal dominant leukodystrophy and Marinesco-Sjögren syndrome

    Författare :Johannes Finnsson; Raili Raininko; Eva Kumlien; Isabella Björkman-Burtscher; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukoencephalopathies; hereditary central nervous system demyelinating diseases; autonomic dysfunction; adult-onset; neuromuscular disease; pediatric; neuro-ophtalmology; ataxia;

    Sammanfattning : There are approximately 6000 to 8000 rare diseases, each with a prevalence of less than 1 / 10 000, but in aggregate affecting 6 to 8% of the population. It is important to evaluate disease development and progression to know the natural course of any disease. LÄS MER

  5. 4. Immunoregulatory differences between adult onset type 1 diabetes and latent autoimmune diabetes in adults (LADA)

    Författare :Magnus Hillman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; diabetology; secreting systems; Isotype class switch; Endocrinology; LADA; Autoantibodies; Autoimmunity; Type 1 diabetes;

    Sammanfattning : Autoimmune diabetes is characterized by cell mediated autoimmunity against insulin producing beta cells in pancreatic islets. Type 1 diabetes is the major cause of diabetes in children and adolescents and is believed to be mediated by a Thl driven destruction of beta cells. LÄS MER

  7. 5. Long-term effects of growth hormone replacement therapy in growth hormone deficient adults

    Författare :Galina Götherström; Göteborgs universitet; []
    Nyckelord :growth hormone; body composition; bone mass; bone density; muscle strength; lipids; glucose metabolism; adult onset GHD; childhood onset GHD; gender;

    Sammanfattning : Deficiency of growth hormone (GHD) in adults results in abnormal body composition, reduced bone mass and muscle strength, deteriorated cardiovascular risk factors. Short-term GH replacement reverses many of the symptoms associated with adult GHD. LÄS MER