Sökning: "adult peripheral blood"

Visar resultat 1 - 5 av 58 avhandlingar innehållade orden adult peripheral blood.

1. 1. Inhibition of T cell responses to autoantigens and allergens by CD25+ regulatory T cells from thymus, cord and adult blood

   Författare :Kajsa Wing; Göteborgs universitet; []
   Nyckelord :Tolerance; CD25 regulatory T cells; adult peripheral blood; cord blood; thymus; autoimmune disease; allergy;

   Sammanfattning : Autoimmune diseases and allergies are a growing problem in the western world today. Tolerance is primarily established by clonal deletion in the thymus. Despite this auto-reactive T cells are normally present in most individuals, which suggests that mechanisms of peripheral tolerance operate to silence potentially pathogenic T cells. LÄS MER

3. 2. Blood pressure in atrial fibrillation

   Författare :Joakim Olbers; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Introduction: Hypertension is a leading risk factor for cardiovascular morbidity and premature death. Prevalence of hypertension in the adult population in Sweden has been estimated to 27%. Atrial fibrillation (AF) is the most prevalent sustained arrhythmia of clinical relevance with an estimated prevalence of at least 2.9% among adults in Sweden. LÄS MER

4. 3. Regulation of Hematopoietic Stem Cells

   Författare :Emma Rörby; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; hematopoietic stem cells; hematopoietic stem cell expansion; cord blood; transforming growth factor beta; Smad signaling; pigment epithelium derived factor; CD9;

   Sammanfattning : This thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. LÄS MER

5. 4. Separation and Further Characterization of Hematopoietic Cell Populations Based on Phenotypic and Biophysical Properties

   Författare :Josefina Dykes; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Blood Group; ABO-system; Hematopoietic Stem Cell Transplantation; Cell Separation;

   Sammanfattning : Hematopoietic stem cells (HSC) are multipotent and possess self-renewal capacity. Thus, they can sustain a life-long hematopoiesis and are also capable of restoring the hematopoietic system when transplanted to a patient. LÄS MER

7. 5. Hyperreactive peripheral neutrophils in periodontitis : FCc receptor activation and plasma proteins

   Författare :Margareta Fredriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Periodontitis neutrophils; oxygen radicals; smoking; priming.;

   Sammanfattning : It is now well established that adult and juvenile periodontitis are associated with a hyperreactivity of the peripheral neutrophils when measured as increased generation of free oxygen radicals after stimulation of the Fcgamma-receptors. Aim: The aims of these investigations were to study if the increased radical generation was: 1) located intra- or extracellularly and attributed to a specific oxygen species or various activation pathways, 2) connected with "priming" (pre-stimulation only disclosed by a secondary activation), 3) associated with systemic aberrations in plasma parameters induced by the periodontal disease or cigarette smoking or 4) related to the neutrophil production of the cytokines IL-8 and TNFalpha after stimulation. LÄS MER