Sökning: "adrenalcortex"

Hittade 1 avhandling innehållade ordet adrenalcortex.

1. 1. Regulation of steroidogenesis : cAMP-dependent transcription in adrenocortical cells

   Författare :Marit Bakke; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :steroid hydroxylases; cyclic AMP; gene regulation; steroidogenesis; adrenalcortex;

   Sammanfattning : Optimal steroid hormone output from the adrenal cortex depends on the peptide hormone ACTH which elicits its effect by increasing the intracellular levels of the second messenger cAMP, and a subsequent activation of the cAMP-dependent protein kinase. An important aspect of ACTH action is the ability of this hormone to increase transcription of a group of genes that encodes the steroid hydroxylases, enzymes that catalyze the conversion of cholesterol to biologically active steroids. LÄS MER