Sökning: "adpeo"

Hittade 3 avhandlingar innehållade ordet adpeo.

1. 1. Functional and structural characterization of the human mitochondrial helicase

   Författare :Jenny Korhonen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mitochondria; mtDNA; replication; replisome; TWINKLE; mtSSB; POL g ; adPEO.;

   Sammanfattning : Mitochondria are the energy producing organelles of the eukaryotic cell. The human mitochondrial DNA (mtDNA) is a double stranded circular molecule of about 16 kb, usually present at 1000-10 000 copies per cell. The genome encodes 13 polypeptides involved in respiration, two ribosomal RNA s and a set of 22 transfer RNA s. LÄS MER

3. 2. Molecular mechanisms of mitochondrial DNA replication

   Författare :Teresa Holmlund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mitochondria; mtDNA; replication; helicase; TWINKLE; POLgamma; POLgammaB; mtSSB; adPEO;

   Sammanfattning : Mitochondria are the energy producing organelles of eukaryotic cells. The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes 13 subunits of the respiratory chain (RC) complexes, two rRNAs and 22 tRNAs. LÄS MER

4. 3. Genetic study of autosomal dominant progressive external ophthalmoplegia and familial myasthenia gravis : linkage analysis, candidate gene cloning and mutation detection

   Författare :Fang-Yuan Li; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Identification of genes responsible for familial human diseases is a major task of medical genetics. In this process, linkage analysis, candidate gene screening and mutation detection are the three major steps (Paper I-VI). LÄS MER