Sökning: "adjuvant treatment"
Visar resultat 11 - 15 av 246 avhandlingar innehållade orden adjuvant treatment.
11. Development of a New Oral Vaccine against Diphtheria and the Study of its Immunogenicity in Mouse and Man
Sammanfattning : Most pathogens enter the body via mucosal surfaces. In contrast to parenterally administered vaccination, mucosal vaccination has the advantage of eliciting both a systemic and a local mucosal immune response. An oral biodegradable adjuvant with these features would have great potential. LÄS MER
12. Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer
Sammanfattning : One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. LÄS MER
13. Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
Sammanfattning : Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the gene expression of the enzyme thymidine phosphorylase (TP), which was related to prognostic factors (paper I, n=254), evaluated as a predictive factor (paper III, n=125), and assessed by change of treatment (paper II, n=28). LÄS MER
14. MYC-driven Medulloblastoma : New Targeted Therapies and Mechanisms of Recurrence
Sammanfattning : Medulloblastoma is the most common malignant brain tumor of childhood. It arises in the posterior fossa but presents with distinct histological and molecular features. Hence, medulloblastoma is divided into four molecular subgroups, WNT, SHH, Group 3, and Group 4. LÄS MER
15. Small breast cancers : Diagnosis, prognostic factors and clinical outcome in a screening population
Sammanfattning : Breast cancer ≤ 10 mm together with ductal in situ cancer of the breast (DCIS) today constitute more than 40% of screening detected breast malignancies. Prognostic factors, diagnosis and clinical outcome for invasive breast cancers ≤ 10 mm and local recurrence in DCIS were evaluated. LÄS MER