Sökning: "adiponectin secretion"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden adiponectin secretion.

1. 1. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes

   Författare :Mozhgan Dorkhan; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; insulin secretion; glucagon test; insulin resistance; insulin glargine; insulin tolerance test; thiazolidinediones; natriuretic peptides; adiponectin; thyroid associated ophthalmopathy; proinsulin;

   Sammanfattning : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. LÄS MER

3. 2. Molecular and physiological regulation of adiponectin exocytosis in white adipocytes

   Författare :Ali Komai; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipocytes; white adipocytes; adiponectin secretion; exocytosis; stimulus-secretion coupling; obesity; diabetes;

   Sammanfattning : .... LÄS MER

4. 3. Pathophysiological regulation of white adipocyte exocytosis of different adiponectin molecular forms

   Författare :Musovic Saliha; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; White adipocytes; adiponectin exocytosis secretion; health and metabolic disease;

   Sammanfattning : In this thesis we have identified mechanisms involved in the exocytosis of different adiponectin molecular forms in health and in metabolic disease. We have also studied similarities and differences in depot-specific adipocyte adiponectin release. LÄS MER

5. 4. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

   Författare :Louise Nilsson; Göteborgs universitet; []
   Nyckelord :prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

   Sammanfattning : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. LÄS MER

7. 5. Ghrelin action on gastrointestinal functions and appetite in rat and man

   Författare :Fredrik Levin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ghrelin; ghrelin-receptors; gastrointestinal motility; migrating myoelectric complex; gastric acid secretion; gastric emptying; appetite; food intake; disinhibition; restraint; hunger; obesity;

   Sammanfattning : To study the effect of ghrelin on the contractility of smooth muscle strips in vitro as well as the effects on fasting small bowel motility and acid secretion in vivo in rats and gastric emptying in rats and humans. To study the effect of peripherally administered ghrelin on plasma levels of glucose, insulin, glucagon, orexin A (OXA), somatostatin and gastrin in rats and ghrelin, cholecystokinin (CCK), glucagonlike peptide-1 (GLP-1), peptide YY (PYY) and motilin in humans. LÄS MER