Sökning: "adhesin"

Visar resultat 1 - 5 av 61 avhandlingar innehållade ordet adhesin.

  1. 1. Helicobacter pylori adhesion and patho-adaptation the role of BabA and SabA adhesins in persistent infection and chronic inflammation

    Författare :Jafar Mahdavi; Umeå universitet.; [2004]
    Nyckelord :H. pylori; BabA; adhesin; Lewis b; MUC5AC; sialyl-dimeric-Lewis x; chronic inflammation; SabA; Lewis x; LPS; odontologi; Odontology;

    Sammanfattning : Helicobacter pylori (H. pylori) is a human-specific gastric pathogen which is responsible for a spectrum of diseases ranging from superficial gastritis to gastric and duodenal ulceration, and which is also highly associated with gastric cancer. The pathogenesis of severe gastric disorders caused by H. LÄS MER

  2. 2. Adaptation of Helicobacter pylori Adherence Properties in Promotion of Host Tropism and Inflammatory Disease

    Författare :Marina Aspholm; Umeå universitet.; [2004]
    Nyckelord :H. pylori; BabA; SabA; adhesin; blood group antigens; sialylated; phase variation; hemagglutination; selectin; adaptation; odontologi; Odontology;

    Sammanfattning : Being among the most prevalent of persistent infectious agents in humans worldwide, Helicobacter pylori induces chronic inflammation (gastritis), which may progress to peptic ulceration and stomach cancer. The ability to adhere to the gastric mucosa is considered to be both a colonization and virulence property of H. pylori. For adherence, H. LÄS MER

  3. 3. Structural characterization of proteins to investigate their roles in diseases: Focus on MID & LTA4H

    Detta är en avhandling från Department of Chemistry, Lund University

    Författare :Mahmudul Hasan; Lund University.; Lunds universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Moraxella IgD binding protein; adhesin; leukotriene A4 hydrolase; small angle x-ray scattering; crystallography; circular dichroism;

    Sammanfattning : Protein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug design and for structure based functional studies. LÄS MER

  4. 4. Structural studies of the surface adhesin SspB from Streptococcus gordonii

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Nina Forsgren; Umeå universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus gordonii; X-ray crystallography; surface adhesin; dental plaque; structural biology; NATURAL SCIENCES Chemistry Biochemistry Structural biology; NATURVETENSKAP Kemi Biokemi Strukturbiologi; ODONTOLOGY; ODONTOLOGI; odontologi; Odontology;

    Sammanfattning : Surface proteins on microorganisms that build up the oral biofilm are key players in the formation of the biofilm. Antigen I/II proteins are surface adhesins found on virtually all oral streptococci and share a conserved multi-domain architecture. These adhesins bind surface components on other bacteria and on host cells. LÄS MER

  5. 5. Of spiders, bugs, and men Structural and functional studies of proteins involved in assembly

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Wangshu Jiang; Uppsala universitet.; [2018]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein assembly; sulfate transporter; crystallography; Proteus mirabilis; fimbriae; adhesin; urinary tract infection; biofilm; spider silk; asymmetric dimer; Bri2; BRICHOS; molecular chaperone; Alzheimer s disease; amyloid; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.Sulfate is a common source of sulfur for cysteine synthesis in bacteria. LÄS MER