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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Studies of gene fusions and copy number alterations in salivary and adnexal neoplasms

    Författare :Marta Persson; Göteborgs universitet; []
    Nyckelord :cancer genetics; fusion oncogenes; chromosome translocation; MYB; NFIB; CRTC1; MAML2; salivary gland; breast; adenoid cystic carcinoma; mucoepidermoid carcinoma; hidradenoma;

    Sammanfattning : Cancer is a genetic disease caused by the accumulation of genetic changes such as mutations and chromosomal rearrangements. An increasing number of genetic studies of both hematological and solid neoplasms have shown that recurrent chromosome translocations often result in fusion oncogenes. LÄS MER

  3. 2. Aspects on Head and neck Cancer with special reference to Salivary Gland Tumours and Single Nucleotide Polymorphism

    Författare :Lena Cederblad; Göran Laurell; Gunilla Enblad; Erik Blomquist; Claes Mercke; Uppsala universitet; []
    Nyckelord :salivary gland carcinoma; adenoid cystic; mucoepidermoid; polymorphous low-grade carinoma; c-myc; cyclin D1; perineural;

    Sammanfattning : A thesis on Head and neck cancer focusing on dose planning, salivary gland carcinoma and Single nucleotide polymorphism.For dose planning PET/CT (Positron emissions tomography/computed tomography) with tracer gave more precise information in comparison dose planning with CT. LÄS MER

  4. 3. Transcriptomic and functional studies of fusion oncogene-driven salivary gland tumors

    Författare :Maryam K. Afshari; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fusion oncogene; MYB; NFIB; PLAG1; HMGA2; adenoid cystic carcinoma; pleomorphic adenoma; targeted therapy;

    Sammanfattning : Fusion genes are potent oncogenic drivers resulting from exchange of regulatory/coding sequences between two genes. They were originally identified in leukemias but are now recognized as key oncogenic events also in many solid tumors, including salivary gland tumors (SGTs). LÄS MER

  5. 4. Diagnostic and prognostic markers in primarily non-smoking related head and neck cancer

    Författare :Mark Zupancic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Head and neck cancer (HNC) includes cancers of the oral cavity, the pharynx (i.e., the nasopharynx, the oropharynx, and the hypopharynx), the larynx, the nasal cavity, the paranasal sinuses, and the salivary glands. LÄS MER

  7. 5. Inverted papilloma and sinonasal malignancies in Sweden

    Författare :Alexandra Elliot; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Sinonasal malignancies (SNMs) are rare and in Sweden they account for approximately 0,1% of all malignancies and 5% of all head and neck malignancies. Apart from sinonasal malignant melanoma (SNMM), their incidence has been reported to decrease since 1960 while the survival rates have remained rather stable during the same time-period. LÄS MER