Sökning: "acyl migration"

Hittade 4 avhandlingar innehållade orden acyl migration.

  1. 1. Enzymatic Synthesis of Mixed Acid Phospholipids

    Författare :Dietlind Adlercreutz; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lysophosphatidylcholine; phosphatidylcholine; acyl migration; equilibrium; organic solvent; lipase; phospholipase; Biotechnology; Bioteknik;

    Sammanfattning : Mixed acid phospholipids are valuable compounds, which are used mainly in membrane- and lipoprotein research and in liposome technology. The chemical synthesis of these special lipids is rather difficult and involves both toxic chemicals and harsh reaction conditions, which makes the products less attractive for medical and biological applications. LÄS MER

  2. 2. Ruthenium-catalyzed redox reactions and lipase-catalyzed asymmetric transformations of alcohols

    Författare :Michaela Edin; Jan-E. Bäckvall; Manfred T. Reetz; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; ruthenium; lipase; catalysis; alcohols; diols; Chemistry; Kemi;

    Sammanfattning : The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining ruthenium-catalyzed redox reactions that lead to racemization or epimerization and lipase-catalyzed asymmetric trans-formations in one-pot.A mechanistic study of the unexpected facile formation of meso-diacetate products found in enzyme-catalyzed acetylations of alkanediols with Candida antarctica lipase B (CALB) was first performed. LÄS MER

  3. 3. Deracemization of Functionalized Alcohols via Combined Ruthenium and Enzyme Catalysis

    Författare :Ann-Britt L. Fransson; Jan-Erling Bäckvall; Hans-Erik Högberg; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : The major part of this thesis describes the synthesis of enantiopure alcohols and diols by combining ruthenium-catalyzed racemization or epimerization and lipase-catalyzed asymmetric transformations. A minor part of this thesis is focused on ruthenium-catalyzed redox reactions for transfer hydrogenation of 1,3-cycloalkanediketones. LÄS MER

  4. 4. Localisation of Fluorescent Probes and the estimation of Lipid Nanodomain sizes by modern fluorescence techniques

    Författare :Radek Sachl; Lennart B-Å Johansson; Martin Hof; Mats Almgren; Tomas Obsil; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Electronic energy transfer; fluorescence; rafts; lipid bilayer; bicelles; micelles; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : The thesis is divided into two major parts. The first part focuses on the localisation of probes in lipid/polymeric bilayers and in GM1 micelles. Included in this thesis is a new approach based on electronic energy transfer/migration (FRET/DDEM), which efficiently determines transversal positions of fluorescent molecules in lipid bilayers. LÄS MER