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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.

1. 1. The relative acute systemic toxicity of selected local anesthetic agents

   Författare :Hal S. Feldman; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

3. 2. Mesoporous magnesium carbonate : Synthesis, characterization and biocompatibility

   Författare :Sara Frykstrand Ångström; Maria Strømme; Johan Gómez de la Torre; Natalia Ferraz; Mika Lindén; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mesoporous; magnesium carbonate; pore size control; cytotoxicity; in vivo; skin irritation; acute systemic toxicity; hemocompatibility; Ca2 uptake; solubility enhancement; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

   Sammanfattning : Mesoporous materials constitute a promising class of nanomaterials for a number of applications due to their tunable pore structure. The synthesis of most mesoporous materials involves a surfactant liquid crystal structure to form the pores. LÄS MER

4. 3. Estimation of acute toxicity by using the differentiated neuronal progenitor C17.2 cell model

   Författare :Jessica Lundqvist; Anna Forsby; Ann-Kristin Östlund Farrants; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurotoxicity; C17.2; cell membrane potential; Optimisation culture condition; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The authorities in Europe and United States request information regarding possible toxicity for substances that are produced in one tonne or more per year. Estimation of acute systemic toxicity is conducted in vivo using mice or rats. LÄS MER

5. 4. Aspects on optimisation of High Dose Methotrexate treatment in children with Acute Lymphoblastic Leukaemia

   Författare :Peter Jönsson; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; high dose methotrexate; exposure; dosing algorithms; renal function; cerebrospinal fluid; childhood acute lymphoblastic leukaemia; population pharmacokinetics; relapse risk;

   Sammanfattning : Childhood Acute Lymphoblastic Leukaemia (ALL) has a unique place in the history of oncology, as it was the first cancer to be cured by drugs. It is therefore an important model upon which concepts of chemotherapy in other malignancies have been developed. Methotrexate is a major component of most contemporary childhood ALL treatment protocols. LÄS MER

7. 5. Immunoregulation by mononuclear phagocytes. Mechanisms and clinical implications

   Författare :Ana Romero; Göteborgs universitet; []
   Nyckelord :;

   Sammanfattning : The cytotoxic effector lymphocytes of the immune system, the natural killer (NK) cells and the CD8+ T lymphocytes (CTL), have been ascribed a pivotal role in defense against malignancy. However, the function of these cells is frequently compromised, in particular at sites of malignant cell expansion. LÄS MER