Sökning: "acute promyelocytic leukemia"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden acute promyelocytic leukemia.

  1. 1. Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry

    Författare :Lovisa Vennström; Göteborgs universitet; []
    Nyckelord :Acute leukemia; population-based; incidence; survival; acute myeloid leukemia; acute lymphoblastic leukemia; acute promyelocytic leukemia; early death;

    Sammanfattning : Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features. LÄS MER

  3. 2. Molecular alterations and clonal evolution in acute myeloid leukemia : prognostic and therapeutic implications

    Författare :Xiaolu Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic stem cells characterized by inhibition of differentiation, subsequent accumulation of incomplete matured cells at various stages and reduced production of healthy hematopoietic elements. Despite significant progress, the outcome of AML is variable and often suboptimal. LÄS MER

  4. 3. In vitro studies of retinoids and arsenic in non-M3 acute myeloid leukemia

    Författare :Sören Lehmann; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Huddinge University Hospital Department of Medicine; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Despite advances in the treatment of patients with acute myeloid leukemia (AML), the majority of the patients will die from their disease. The current intensive therapy for AML is also complicated my substantial morbidity and mortality and, as a result, many patients cannot be given the most effective therapy. LÄS MER

  5. 4. Telomeres and telomerase and their functional applications in myeloproliferative neoplasms and acute myeloid leukemia

    Författare :Jenny Dahlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Myeloproliferative neoplasms (MPNs) are a group of diseases characterized by hyperproliferation in the myeloid lineages of the bone marrow, leading to increased levels of circulating mature blood cells from one or more lineages. MPNs consist of polycythemia vera, essential thrombocythemia and primary myelofibrosis. LÄS MER

  7. 5. The SHB adaptor protein in human and murine leukemia

    Författare :Maria Jamalpour; Michael Welsh; Edvard Smith; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : The SHB adaptor protein operates downstream of tyrosine kinase receptors. It has been found previously that Shb deficiency in hematopoietic stem cells (HSCs) results in less proliferation and failure to maintain the myeloid compartment over time. LÄS MER