Sökning: "acute lymphoblastic leukemia"
Visar resultat 16 - 20 av 82 avhandlingar innehållade orden acute lymphoblastic leukemia.
16. Vascular density and bone marrow fibrosis in childhood acute lymphoblastic leukemia
Sammanfattning : Background: In childhood acute lymphoblastic leukemia (ALL), the cure rate has now reached 80% in the western world. Even so, 15¬–20% will die from the disease or treatment-related causes, among them children who did not present any known unfavorable features at diagnosis. LÄS MER
17. Optimizing Chemotherapy in Childhood Acute Myeloid Leukemia
Sammanfattning : Despite major advances in our understanding of the biology of childhood acute myeloid leukemia (AML) and the development of new cytotoxic drugs, the prognosis of long-term survival is still only 60-65 %.In the present research, we studied the pharmacokinetics of drugs used in the induction therapy of childhood AML and performed in vitro drug sensitivity testing of leukemic cells from children with AML. LÄS MER
18. Unwinding the layers of high hyperdiploid childhood acute lymphoblastic leukemia
Sammanfattning : .... LÄS MER
19. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia
Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. LÄS MER
20. Mechanisms of therapy resistance in acute lymphoblastic leukemia
Sammanfattning : Acute lymphoblastic leukemia (ALL) is a highly aggressive pediatric cancer that can affect both B cells and T cells. The advent of new therapies has increased the cure rates for both B-ALL and T-ALL patients. However, some patients still experience relapse with a variable response to the treatment and display poor survival. LÄS MER