Sökning: "activity type"

Visar resultat 1 - 5 av 1756 avhandlingar innehållade orden activity type.

  1. 1. Bone mass and physical activity

    Författare :Anna Nordström; Tommy Olsson; Peter Nordström; Heather McKay; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; physical activity; peak bone mineral density; males; fractures; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Abstract Weak and osteoporotic bones in old age are an increasing cause of mortality and painful physical impairment of the elderly, especially in the western world. Bone mineral accrual during childhood and adolescence is thought to play a vital role in preventing osteoporosis. LÄS MER

  3. 2. Beta-Glycosidases from Hyperthermophiles as Biocatalysts

    Författare :Therese Hansson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biochemical technology; Biokemisk teknik; Proteins; enzymology; Proteiner; enzymologi; Biotechnology; high temperatures; water activity; activity; selectivity; hexanol; hexyl-b-glycoside; galacto-oligosaccharides; lactose; hyperthermostable b-glycosidase; hydrolysis; optimisation; transglycosylation;

    Sammanfattning : The thesis concerns glycosyl transfer with use of b-glycosidases, most of them from hyperthermophilic organisms. Both optimisation of the reaction conditions and protein engineering in terms of site-directed mutagenesis were used to improve b-glycosidase-catalysed reactions. LÄS MER

  4. 3. Physical Activity and Cardiovascular Disease

    Författare :Kasper Andersen; Johan Sundström; Claes Held; Frieder Braunschweig; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical activity; epidemiology; cohort study; heart failure; cardiovascular disease; arrhythmias; atrial fibrillation; bradyarrhythmias; sudden cardiac death; heart failure; stroke; ischemic heart disease; cardiovascular death; maximal exercise capacity; muscle strength; skeletal muscle morphology; Kardiologi; Cardiology; Epidemiology; Epidemiologi;

    Sammanfattning : The aim was to investigate associations of fitness and types and levels of physical activity with subsequent risk of cardiovascular disease.Four large-scale longitudinal cohort studies were used. The exposures were different measures related to physical activity and the outcomes were obtained through linkage to the Swedish In-Patient Register. LÄS MER

  5. 4. Ligands of the Angiotensin II Type 2 Receptor : Exploring structure and function of the AT2R ligand C38

    Författare :Rebecka Isaksson; Mats Larhed; Annette Bayer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiotensin II type 2 receptor; AT2R antagonists; sulfonyl carbamates; bicyclic amides; metabolic stability; functional activity assay; pharmacological profile; medicinal chemistry; structure-activity relationship; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : The renin-angiotensin-aldosterone-system (RAAS) control blood-pressure regulation, exerted by the main effector peptide angiotensin II (AngII) binding the angiotensin II type 1 receptor (AT1R). While hypertension is the most known disease caused by over-activity in RAAS, several proteins in the system exhibit protective functions. LÄS MER

  7. 5. Body Composition in Adolescents with Type 1 Diabetes : Aspects of Glycaemic Control and Insulin Sensitivity

    Författare :Stefan Särnblad; Jan Åman; Torsten Tuvemo; Jan Bolinder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; Type 1 diabetes mellitus; Adolescent; Body composition; Physical activity; Energy intake; Metformin; Insulin sensitivity; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Sammanfattning : Excessive weight gain has frequently been reported in adolescents with type 1 diabetes, especially in girls. In general, puberty is associated with reduced insulin sensitivity that is further diminished by overweight. The causes and consequences of excessive weight gain in adolescents with type 1 diabetes are not fully understood. LÄS MER