Sökning: "activity dependent"

Visar resultat 6 - 10 av 1786 avhandlingar innehållade orden activity dependent.

1. 6. Lysophosphatidic acid : Physiological effects and structure-activity relationships

   Författare :Ulrika K. Nilsson; Samuel Svensson; Karin E. Bornfeldt; Linköpings universitet; []
   Nyckelord :Lysophospholipids pharmacology; physiology; structure-activity relationship; muscle; smooth; drug effects; myometrium; norepinephrine; epinephrine; signal transduction; MEDICINE; MEDICIN;

   Sammanfattning : Lipids havepreviously been considered primarily as building blocks of the cell membrane, but are now also recognized as important cell signaling molecules. Lysophosphatidic acid (LPA) is a glycerophospholipid consisting of a phosphate head group, a linker region, and a lipophilic tail. LÄS MER

3. 7. Nuclease Activity as a Biomarker in Cancer Detection

   Författare :Alien Balian; Frank Hernandez; Kajsa Uvdal; Baris Ata Borsa; Ester Boix Borrás; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nucleases; Nuclease activity; Cancer detection; Diagnosis; Oligonucleotides; Nucleic acid probes; MRI-probes; Activatable probes;

   Sammanfattning : Nucleases are a group of enzymes that cleave the phosphodiester bonds in nucleic acids. As such, nucleases act as biological scissors that exhibit a plethora of fundamental roles, in prokaryotes and eukaryotes, dependent or non-dependent on their catalytic capability. LÄS MER

4. 8. Towards molecular weight-dependent uses of kraft lignin

   Författare :Ayumu Tagami; Mikael Lindström; Olena Sevastyanova; Anna Wistrand; Stefan Backa; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; kraft lignin; successive solvent fractionation; molecular weight; structural analysis; thermal stability; heat capacity; antioxidant activity; methylene blue sorption; tunicate cellulose nanofiber-starch lignin composites films; film properties; Fiber- och polymervetenskap; Fibre and Polymer Science;

   Sammanfattning : There is growing demand for a more efficient use of polymers that originate from renewable feedstocks due to the depleting supply of fossil fuels, based on economic and environmental reasons. As a result, lignin has attracted renewed interest as a resource for various bioproducts. LÄS MER

5. 9. Activity-regulated retinoic acid signaling in olfactory sensory neurons

   Författare :Hande Login; Staffan Bohm; Mattias Alenius; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mouse olfactory system; RA; neuronal activity; CNG; Cyp26B1; BACE1; Kirrel-2; molekylärbiologi; Molecular Biology;

   Sammanfattning : The aim of the studies included in the thesis is to better understand the interplay between neuronal activity-dependent gene regulation and the bioactive vitamin A metabolite all-trans-retinoic acid (RA) during postnatal development, refinement and maintenance of precise neuronal connectivity using the olfactory sensory neuron (OSN) in the olfactory epithelium (OE) of genetically modified mice as a model. We show that:Inhibition of RA receptor (RAR)-mediated transcription in OSNs reduces expression of the olfactory cyclic nucleotide-gated (CNG) ion channel, which is required for odorant receptor (OR)-mediated stimulus transduction. LÄS MER

7. 10. Predator effects on behaviour and life-history of prey

   Författare :Tomas Brodin; Frank Johansson; Bradley Anholt; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; activity; behaviour; behavioural syndromes; damselfly; development; growth; life-history; predator-prey interaction; predation risk; thinning; Freshwater ecology; Limnisk ekologi;

   Sammanfattning : In this thesis I investigate predator-induced effects on behavioural and life-history characteristics of prey. At any moment a given predator is capable of attacking a small number of prey. LÄS MER