Sökning: "activity dependent"

Visar resultat 1 - 5 av 1610 avhandlingar innehållade orden activity dependent.

  1. 1. Stroke recovery activity-dependent mechanisms

    Författare :Miriana Quattromani; Neurokirurgi; []
    Nyckelord :Stroke recovery; Photothrombosis; Enriched environment; Bioluminescence imaging; Toll-like receptor 2; Microglia; Neurons; Extracellular matrix; Perineuronal nets; Aggrecan; Proteases; Parvalbumin; Resting-state functional connectivity;

    Sammanfattning : Stroke is the leading cause of disability in developed countries and among the major causes of death worldwide. During a stroke, neurons deprived of their normal metabolic substrates cease to function in seconds and show signs of structural damage after only a few minutes which result in the impairment of sensory and motor function. LÄS MER

  2. 2. Physical activity assessed by accelerometry in children

    Författare :Andreas Nilsson; Karin Piehl-Aulin; Ulf Ekelund; Gareth Stratton; Örebro universitet; []
    Nyckelord :AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; activity patterns; adolescents; health promotion; activity monitor; sedentary; Medicine; Medicin; Biomedicin; Biomedicine;

    Sammanfattning : Physical activity (PA) is likely to constitute an important aspect of health-related behaviour in growing children. However, the knowledge on levels and patterns of PA in children is limited, due to the difficulty of precisely measuring this complex behaviour in normal daily living. LÄS MER

  3. 3. ON THE EFFICIENCY OF DISPLACEMENT VENTILATION, with Particular Reference to the Influence of Human Physical Activity

    Författare :Magnus Mattsson; Högskolan i Gävle; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ENGINEERING AND TECHNOLOGY; Displacement ventilation; Ventilation efficiency; Physical activity; Human activity; Movements; Transient behaviours; Ceiling height; Wall temperature.; Building engineering; Byggnadsteknik; Fluid mechanics; Strömningsmekanik;

    Sammanfattning : The efficiency of room ventilation by the displacement principle was studied with respect to some influential factors, in particular that of physical activity. The study was experimental and performed in two full-scale test rooms, one of office-size and one of classroom-size. LÄS MER

  4. 4. Anticancer Activity of Melflufen : Preclinical Studies of a Novel Peptidase-Potentiated Alkylator

    Författare :Sara Strese; Joachim Gullbo; Rolf Larsson; Mårten Fryknäs; Sigurd Vitols; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; cancertherapy; preclinical studies; melflufen; aminopeptidase-potentiated; cancer; angiogenesis; Klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : Melflufen (melphalan flufenamide, chemical name L-melphalanyl-p-L-fluorophenylalanine ethyl ester hydrochloride, previously called J1) is a derivative of the classical alkylating agent melphalan. Melflufen is potentiated by hydrolytic cleavage by aminopeptidase N (APN), leading to high intracellular concentrations of alkylating moieties and subsequent cell death. LÄS MER

  5. 5. Lysophosphatidic acid : Physiological effects and structure-activity relationships

    Författare :Ulrika K. Nilsson; Samuel Svensson; Karin E. Bornfeldt; Linköpings universitet; []
    Nyckelord :Lysophospholipids pharmacology; physiology; structure-activity relationship; muscle; smooth; drug effects; myometrium; norepinephrine; epinephrine; signal transduction; MEDICINE; MEDICIN;

    Sammanfattning : Lipids havepreviously been considered primarily as building blocks of the cell membrane, but are now also recognized as important cell signaling molecules. Lysophosphatidic acid (LPA) is a glycerophospholipid consisting of a phosphate head group, a linker region, and a lipophilic tail. LÄS MER