Sökning: "activated platelets"

Visar resultat 11 - 15 av 64 avhandlingar innehållade orden activated platelets.

1. 11. Attenuation of acute inlammatory responses by surface nanotopography

   Författare :Mats Hulander; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gold nanoparticles; nanotopography; gradient nanotopography; immune complement; platelets;

   Sammanfattning : The interaction between biology and non-viable surfaces is crucial for many organisms and cells. For example, bacterial cells need to adhere to mineral surfaces in the soil, plants climb and adhere to walls and marine organisms produce adhesives to cling to underwater rocks etc. LÄS MER

3. 12. Effect of Surface Nanotopography on Blood-Biomaterial Interactions

   Författare :Natalia Ferraz; Marjam Ott; Jaan Hong; Jan Carlsson; Tom Eirik Mollnes; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanoporous alumina; nanotopography; biomaterial; platelets; complement system; macrophages; whole blood; inflammatory response; Chemistry; Kemi; Immunobiology; Immunbiologi; Immunologi; Immunology; Materialvetenskap; Materials Science;

   Sammanfattning : Biologically inspired materials are being developed with the aim of improving the integration of medical implants and minimizing non-desirable host reactions. A promising strategy is the design of topographically patterned surfaces that resemble those found in the extracellular environment. LÄS MER

4. 13. On Neutrophil and Platelet Adhesive Interactions in Septic Lung Injury

   Författare :Asad Muhammad; Kirurgi; []
   Nyckelord :Leukocytes; chemokines; platelets; lung; sepsis;

   Sammanfattning : Sepsis induced by intestinal perforation is a life-threatening illness and is a frequent cause of leukocyte-mediated lung injury. Although antimicrobial therapy has been the central clinical strategy for these patients, the survival rates in such patients are still very low because of their impaired host defense mechanisms. LÄS MER

5. 14. Interactions between platelets and complement with implications for the regulation at surfaces

   Författare :Per H. Nilsson; Kristina Nilsson Ekdahl; John Lambris; Ian Nicholls; Berhane Ghebrehiwet; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system activation; regulation ; platelets activation; regulation ; biomaterials; biocompatibility; chondroitin sulfate-A; apyrase; C1q; C3; factor H; C4BP; ADP; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Disturbances of host integrity have the potential to evoke activation of innate immunologic and hemostatic protection mechanisms in blood. Irrespective of whether the activating stimulus is typically immunogenic or thrombotic, it will generally affect both the complement system and platelets to a certain degree. LÄS MER

7. 15. The role of platelets in whole blood coagulation

   Författare :Sofia Ramström; Nils Olav Solum; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The body's first line of defence against bleeding is the platelets, small cell fragments with multiple roles in the coagulation process. The platelets are patrolling our blood vessels, looking for damage in the endothelial cell layer, to which they attach and transform, recruit more platelets and assemble the plasma coagulation proteases on their surfaces. LÄS MER