Sökning: "actin polymerization"
Visar resultat 6 - 10 av 44 avhandlingar innehållade orden actin polymerization.
6. Structural Study of the WH2 Family and Filamin: Implications for Actin Cytoskeleton Regulation
Sammanfattning : Cellular processes like motility, chemotaxis, phagocytosis and morphogenesis are dependent on the dynamic regulation of the actin cytoskeleton. This cytoskeleton system is tightly controlled by a number of diverse actin-binding proteins (ABPs) by various mechanisms described as nucleation, polymerization, capping, severing, depolymerization and sequestration. LÄS MER
7. Profilin : From the Cell Edge into the Nucleus
Sammanfattning : Internal and external signaling dependent changes in cell behavior are directly linked to force-generating remodeling of the actin microfilament system which is juxtaposed to the inside of the plasma membrane. This dynamic filament system is involved in many processes in the cytoplasm and the nucleus of eukaryotic cells. LÄS MER
8. Profilins : The Control of the Microfilament and Microtubule systems
Sammanfattning : The microtubule and actin filament systems are important for many cellular processes such as intracellular organelle trafficking, cell adhesion, migration and mitosis. The two filament systems are closely connected, operate in parallel and are essential for proper cell function. LÄS MER
9. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling
Sammanfattning : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. LÄS MER
10. Elements in regulation of the microfilament system
Sammanfattning : This thesis deals with cell motility. The process of rapid actin polymerization in the lamellipodium of a migrating cell is responsible for its protrusion. Studies have been made on some of the elements behind this event and special interest has been focused on the protein tropomyosin. LÄS MER