Sökning: "actin polymerization"

Visar resultat 6 - 10 av 44 avhandlingar innehållade orden actin polymerization.

  1. 6. Structural Study of the WH2 Family and Filamin: Implications for Actin Cytoskeleton Regulation

    Författare :Adeleke H. Aguda; Robert Robinson; Lars Rask; Lars Backman; Uppsala universitet; []
    Nyckelord :Biochemistry; Actin; Thymosin; Ciboulot; N-WASP; Filamin; Calponin homology domain; WH2; Protein Crystallography; Biokemi;

    Sammanfattning : Cellular processes like motility, chemotaxis, phagocytosis and morphogenesis are dependent on the dynamic regulation of the actin cytoskeleton. This cytoskeleton system is tightly controlled by a number of diverse actin-binding proteins (ABPs) by various mechanisms described as nucleation, polymerization, capping, severing, depolymerization and sequestration. LÄS MER

  3. 7. Profilin : From the Cell Edge into the Nucleus

    Författare :Sara Sadi; Roger Karlsson; Maria Vartiainen; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; profilin; actin; microfilament system; nucleus; SRF; MRTF; MAL; transcription; microtubules; Cell Biology; cellbiologi;

    Sammanfattning : Internal and external signaling dependent changes in cell behavior are directly linked to force-generating remodeling of the actin microfilament system which is juxtaposed to the inside of the plasma membrane. This dynamic filament system is involved in many processes in the cytoplasm and the nucleus of eukaryotic cells. LÄS MER

  4. 8. Profilins : The Control of the Microfilament and Microtubule systems

    Författare :Michaela Nejedla; Roger Karlsson; Klemens Rottner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Profilin; Actin; Microtubules; Cell Biology; cellbiologi;

    Sammanfattning : The microtubule and actin filament systems are important for many cellular processes such as intracellular organelle trafficking, cell adhesion, migration and mitosis. The two filament systems are closely connected, operate in parallel and are essential for proper cell function. LÄS MER

  5. 9. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

    Författare :Sebastian Albinsson; Kärlfysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; cytochemistry; histochemistry; wall stress; shear stress; hypertension; Histology; differentiation; growth; caveolin; smooth muscle; actin; Fysiologi; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. LÄS MER

  7. 10. Elements in regulation of the microfilament system

    Författare :Louise Hillberg; Uno Lindberg; Theresia Stradal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell motility; microfilament system; actin; tropomyosin; Cell and molecular biology; Cell- och molekylärbiologi; Cell Biology; cellbiologi;

    Sammanfattning : This thesis deals with cell motility. The process of rapid actin polymerization in the lamellipodium of a migrating cell is responsible for its protrusion. Studies have been made on some of the elements behind this event and special interest has been focused on the protein tropomyosin. LÄS MER