Sökning: "actin cytoskeleton"

Visar resultat 11 - 15 av 132 avhandlingar innehållade orden actin cytoskeleton.

1. 11. Characterization of New Players in Planar Polarity Establishment in Arabidopsis

   Författare :Stefano Pietra; Markus Grebe; Niko Geldner; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SABRE; planar polarity; CLASP; cell division orientation; microtubule cytoskeleton; actin; AIP1; patterning; Developmental Biology; miljömedicinsk utvecklingsbiologi;

   Sammanfattning : Coordinated polarity and differentiation of cells in the plane of a tissue layer are essential to the development of multicellular organisms. Arabidopsis thaliana root hairs and trichomes provide model systems to study the pathways that control planar polarity and cell fate specification in plants. LÄS MER

3. 12. Structure and function of the cytoskeleton in cardiac and skeletal muscle

   Författare :Johanna Balogh; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP-receptor; Cardiovascular system; Kardiovaskulära systemet; cardiomyopathy; transgenic mice; skeletal muscle; heart; muscle contraction; cytoskeleton; desmin;

   Sammanfattning : We have examined the functional and structural roles of the cytoskeletal protein desmin in cardiac and skeletal muscles using a genetically modified mouse (Des-/-) with the desmin gene ablated. Desmin forms filaments at the Z-disks in the striated muscle sarcomere, have connections to the sarcolemma and most likely align sarcomeres and whole cells. LÄS MER

4. 13. Mechanisms for TGF-β-Mediated Regulation of the Actin Filament System and Apoptosis

   Författare :Sofia Edlund; Pontus Aspenström; Maréne Landström; Tommy Andersson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; TGF-beta; cytoskeleton; GTPases; mitogen-activated protein kinase kinase 3; TGF-beta-activated kinase 1; Apoptosis; Smad7; beta-catenin; p38 MAPK; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participate in many different types of cellular processes, such as growth inhibition, cell migration, differentiation, cell adhesion, wound healing and immunosuppression. Alterations of TGF-β superfamily signalling results in several different disorders, including bone disease, vascular disease and cancer. LÄS MER

5. 14. On the mechanics of actin and intermediate filament networks and their contribution to cellular mechanics

   Författare :Björn Fallqvist; Kroon Martin; Peter McHugh; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; actin; cell; mechanical; constitutive; intermediate; continuum; constitutive; Hållfasthetslära; Solid Mechanics;

   Sammanfattning : The mechanical behaviour of cells is essential in ensuring continued physiological function, and deficiencies therein can result in a variety of diseases. Also, altered mechanical response of cells can in certain cases be an indicator of a diseased state, and even actively promoting progression of pathology. LÄS MER

7. 15. The Extended Role of the Molecular Chaperone CCT

   Författare :Andreas Svanström; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; CCT oligomer; Actin; CCT delta; CCT epsilon; Gelsolin; MRTF-A; Cell morphology;

   Sammanfattning : The oligomeric chaperone CCT is a large ATP-dependent chaperonin that consists of two rings placed back-to-back with eight different paralogous subunits with a size of ~ 55 kDa that sit in each of the two rings. The function of CCT is mainly to fold the abundant proteins actin and tubulin, components of the cytoskeleton. LÄS MER