Sökning: "accessory gene regulator agr"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden accessory gene regulator agr.

  1. 1. The accessory gene regulator, agr, a system for coordinate control of virulence genes in Staphylococcus aureus

    Författare :Eva Morfeldt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bacterial pathogenicity is generally multifactorial, and genes encoding virulence factors are often subject to coordinate regulation. The regulating systems are supposed to adapt the production of virulence factors in response to changes in the environment during the process of infection. LÄS MER

  3. 2. Invasive Staphylococcus aureus infections

    Författare :Gunnar Jacobsson; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; epidemiology; risk factors; clinical presentation; mortality; recurrence; sequelae; agr; serology; colonization;

    Sammanfattning : Staphylococcus aureus is a leading cause of septicaemia-related death. The aims of this thesis were to describe the epidemiology of invasive Staphylococcus aureus infections (ISA), the clinical course, and serological response in ISA in a prospective, population-based study. LÄS MER

  4. 3. Staphylococcus aureus toxins - Influence on food safety and animal health

    Författare :Yusak Budi Susilo; Teknisk mikrobiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Staphylococcus aureus; toxins; food safety; enterotoxin A SEA ; prophage life cycle; GFP reporter strain; flow cytometry; enterotoxin D SED ; accessory gene regulator agr ; bovine mastitis; enterotoxin C SEC ; toxic shock syndrome toxin-1 TSST-1 ;

    Sammanfattning : Staphylococcus aureus (S. aureus) is a notorious opportunistic foodborne pathogen and also a common cause of bovine mastitis. It is known to produce many different virulence factors, including various staphylococcal enterotoxins and toxic shock syndrome toxin-1 (TSST-1). LÄS MER

  5. 4. Regulation of virulence gene expression in Staphylococcus aureus

    Författare :Karin Tegmark Wisell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The pathogenic bacterium Staphylococcus aureus has the ability to cause a wide variety of human diseases, ranging from superficial abscesses and wound infections to deep and systemic infections such as osteomyelitis, endocarditis and septicaemia. The ability to cause disease has been attributed to a large number of toxins and digesting enzymes as well as to proteins at the bacterial surface that bind various host molecules. LÄS MER

  7. 5. Studies on regulatory networks governing virulence gene transcription in Staphylococcus aureus

    Författare :Erik Gustafsson; Högskolan i Skövde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Naturvetenskap; Natural sciences;

    Sammanfattning : Staphylococcus aureus pathogenicity is dependent on the coordinated action of a number of virulence factors and the expression of these virulence factors is determined by several global regulators. The main regulator seems to be agr but there are several additional regulators (mostly sarA homologues) involved that mainly act downstream of agr. LÄS MER