Sökning: "abdominal paraganglioma"
Hittade 5 avhandlingar innehållade orden abdominal paraganglioma.
1. Pheochromocytoma and abdominal paraganglioma : clinical and genetic aspects
Sammanfattning : Pheochromocytomas and abdominal paragangliomas are rare catecholamine producing tumours arising from sympathoadrenal paraganglia located within and outside of the adrenal medulla, respectively. The great majority of tumours are benign and cured by surgery. LÄS MER
2. Incidentally discovered adrenal tumours, adrenal metastases and pheochromocytomas - Clinical and epidemiological aspects
Sammanfattning : With increasing use of high resolution radiological imaging incidentally discovered adrenal tumours (adrenal incidentalomas, AI) have become a common clinical problem. The aim of work-up and follow-up of patients with AI is to detect malignant (primary or metastatic) and/or hormone-producing tumours. LÄS MER
3. Genetic and molecular background of pheochromocytoma and paraganglioma
Sammanfattning : Pheochromocytomas (PCC) and abdominal paragangliomas (PGL), collectively denoted PPGL, are neuroendocrine tumors (NET) with a highly diverse genetic and molecular etiology, arisen in the adrenal medulla and abdominal paraganglia respectively. The tumors often cause cardiovascular symptoms due to the high production of catecholamines, and malignancy occurs in 10% of the PCCs and 30% of the PGLs. LÄS MER
4. Further delineation of molecular alterations in adreno-medullary tumors
Sammanfattning : Pheochromocytomas, abdominal paragangliomas and neuroblastomas are tumors of the sympathetic nervous system. Anatomically pheochromocytomas and abdominal paragangliomas arise from sympathoadrenal paraganglia, within and outside the adrenal medulla, respectively. LÄS MER
5. Endocrine tumour development : with special focus on chromosome arms 1p and 11q
Sammanfattning : The overall goal of this thesis has been to characterise the involvement of chromosome arms 1p and 11 q in the development of endocrine tumours. The MEN1 gene was analysed as a candidate tumour suppressor gene by screening for mutations in follicular thyroid tumours, malignant melanomas, pheochromocytomas, and abdominal paragangliomas. LÄS MER