Sökning: "a-Gal"

Hittade 4 avhandlingar innehållade ordet a-Gal.

  1. 1. In vitro models of xenograft rejection : studies on leukocyte-endothelial cell interactions

    Författare :Cecilia Ehrnfelt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Xenotransplantation; endothelium; neutrophils; monocytes; NK cells; a-Gal; antibodies; porcine islets; MCP-1;

    Sammanfattning : Xenotransplantation is the transplantation of cells, tissues or organs between different species and is a potential alternative to allotransplantation because of the lack of human donors. The pig is believed to be a suitable donor-species to man for medical, technical, financial and ethical reasons. LÄS MER

  3. 2. Recombinant mucin-immunoglobulin chimeras as xenoreactive anti-pig antibody absorbers

    Författare :Jining Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human allotransplantation is nowadays the generally accepted treatment of choice for several illnesses leading to organ failure. A major problem facing clinical organ transplantation is the lack of human donor organs and tissues. Xenotransplantation from pig to man is considered a plausible solution to this problem. LÄS MER

  4. 3. Synthesis of inositolphosphoglycans found in Trypanosoma cruzi and development of novel carbohydrate monomolecular layers

    Författare :Markus Hederos; Robert Madsen; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : In this thesis, synthetic carbohydrate chemistry has been utilized to contribute to the fundamental understanding of three biological relevant areas. These include parasite cell-membrane glycoconjugates, protein-resistant surfaces and antifreeze glycoproteins. LÄS MER

  5. 4. Characterization of surface components of Moraxella catarrhalis and pathogenic Neisseria

    Författare :Motiur Rahman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Moraxella catarrhalisantibody LPS NeisseriapiliPilC;

    Sammanfattning : Infection is a multistep process including adhesion, colonisation, invasion and multiplication which finally results in disease. Bacterial surface components and virulence factors are essential for all these different steps and they are co-ordinately regulated during the different steps of pathogenesis and infection. LÄS MER