Sökning: "a westman"

Visar resultat 11 - 15 av 58 avhandlingar innehållade orden a westman.

  1. 11. mPGES-1 and the PGE2 pathway in arthritis

    Författare :Marie Westman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Prostaglandins; mPGES-1; PGES2; cyclooxygenase; rheumatoid arthritis; collagen induced arthritis; antirheumatic treatments; inflammation; synovial tissue; steroids; TNF blockade;

    Sammanfattning : Prostaglandins are a group of lipid mediators derived from essential fatty acids that act on cells in close proximity of their synthesis. Prostaglandins are produced in a cell specific manner by a variety of cells in response to physiological or pathological stimulation. LÄS MER

  3. 12. Host modulation of excessive innate immune responses

    Författare :Johannes Westman; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : A fundamental role of the innate immune system is to elicit a proper response against both invading pathogens and tissue damage or danger signals. Although the innate immune system often is successful in eliminating danger, an excessive host-response can result in severe tissue injury. LÄS MER

  4. 13. Ambiguities and Intertwinings in Teachers' Work : Existential dimensions in the midst of experience and global trends

    Författare :Susanne Westman; Ulf Blossing; Luleå tekniska universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Pedagogik; Education;

    Sammanfattning : The purpose of this thesis was set against the background of changed expectations on education and teachers’ work in contemporary Western societies, reflecting global educational trends of standardisation and assessment moving further down the ages. The overall aim of the thesis was to explore and gain understandings of how teachers’ work is constituted. LÄS MER

  5. 14. Studies of ischemia and reperfusion in muscle and liver on glutathione and amino acid metabolism in man

    Författare :Bo Westman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Oxidative stress increases the formation of reactive oxygen species (ROS), which can induce damage and breakdown of enzymes and lipoproteins. This leads to impaired cellular function and ultimately to death of cells and eventually organ failure. ROS are thought to be responsible for the damage during reperfusion following ischemia. LÄS MER

  7. 15. The impact of protein modification on immunogenicity and arthritogenicity

    Författare :Ewa Westman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Post translational modifications; chlorination; CII; CIA; RA; effect of therapeutic substance CDM for RA;

    Sammanfattning : Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 1% of the Western world population. There are several theories regarding the etiopathogenesis. LÄS MER