Sökning: "Zheng Ge"

Hittade 2 avhandlingar innehållade orden Zheng Ge.

  1. 1. Transcriptional and post-transcriptional regulation of telomerase reverse transcriptase (hTERT) expression : the role of histone modification and alternative splicing

    Författare :Zheng Ge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Telomerase, an RNA-dependent DNA polymerase responsible for telomeric DNA elongation, is silent in most normal differentiated human cells due to the tight repression of its catalytic unit, telomerase reverse transcriptase (hTERT), whereas constitutive hTERT expression and telomerase activation are prerequisites for cellular immortalization/malignant transformation. As reconfiguration of chromatin acts like a master on/off switch, determining whether particular genes are active or inactive, the project was specifically designed to first elucidate molecular strategies that integrate diverse signalling pathways at the hTERT chromatin and consequently result in telomerase activation or repression in normal and malignant human cells. LÄS MER

  3. 2. Molecular sieve films and zoned materials : synthesis and characterization

    Författare :Zheng Wang; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical Technology; Kemisk teknologi;

    Sammanfattning : Molecular sieve films and colloidal particles have great potential for utilization in novel, technological sophisticated applications such as structured catalysts, sensors and membranes. The work in this thesis mainly concerns the synthesis of molecular sieve films and the crystallization of zoned MFI materials. LÄS MER