Sökning: "Zaki Shaikhibrahim"

Hittade 1 avhandling innehållade orden Zaki Shaikhibrahim.

1. 1. Dynamics of protein folding and subunit interactions in assembly of the yeast mediator complex

   Författare :Zaki Shaikhibrahim; Stefan Björklund; Bengt-Harald Jonsson; Umeå universitet; []
   Nyckelord :mediator; transcriptional regulation; assembly; folding; MEDICINE; MEDICIN; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : The Mediator complex was originally discovered in the yeast Saccharomyces cerevisiae and has since then been shown to be required for transcriptional regulation both in vitro and in vivo. The Mediator complex also stimulates basal, unregulated transcription and serves as a bridge by conveying signals from promoter-bound transcriptional regulatory proteins such as activators and repressors to the RNA Polymerase II general transcriptional machinery. LÄS MER