Sökning: "ZFPs"

Hittade 1 avhandling innehållade ordet ZFPs.

1. 1. Transcriptional Silencing in the Imprinted Igf2-H19 Loci: The Mystique of Epigenetics

   Författare :Vasudeva Ginjala; Andreas Paldi; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Imprinting; DNA methylation; IGF2-H19; CTCF; ZFPs; PARP; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Genetics; genetik;

   Sammanfattning : Genomic imprinting marks a subset of autosomal loci expressed in parent of origin-dependent monoallelic expression in a non-Mendelian fashion. To restore totipotency and to reset the imprint according to the sex of the individual, the mark must be erased during germline development. LÄS MER