Sökning: "YopD translocator function in Yersinia pseudotuberculosis type III secretion"

Hittade 4 avhandlingar innehållade orden YopD translocator function in Yersinia pseudotuberculosis type III secretion.

1. 1. YopD translocator function in Yersinia pseudotuberculosis type III secretion

   Författare :Tiago R. D. Costa; Matthew S. Francis; William D. Picking; Umeå universitet; []
   Nyckelord :Y. pseudotuberculosis; T3SS; translocon; YopD; coiled-coil; effector delivery; regulation; virulence; mikrobiologi; Microbiology;

   Sammanfattning : Type III secretion systems (T3SS) are a common feature of Gram-negative bacteria, allowing them to inject anti-host effectors into the interior of infected eukaryotic cells. By this mechanism, these virulence factors help the bacteria to modulate eukaryotic cell function in its favor and subvert host innate immunity. LÄS MER

3. 2. Multiple twists in the molecular tales of YopD and LcrH in type III secretion by Yersinia pseudotuberculosis

   Författare :Petra J Edqvist; Matthew Francis; Olaf Schneewind; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yersinia pseudotuberculosis; T3SS; YopD; translocation process; LcrH; class II chaperone; substrate secretion pathway specificity; Molecular biology; Molekylärbiologi;

   Sammanfattning : The type III secretion system (T3SS) is a highly conserved secretion system among Gram negative bacteria that translocates anti-host proteins directly into the infected cells to overcome the host immune system and establish a bacterial infection. Yersinia pseudotuberculosis is one of three pathogenic Yersinia spp. LÄS MER

4. 3. Biogenesis, function and regulation of the type III secretion translocon of Yersinia pseudotuberculosis

   Författare :Salah I. Farag; Matthew S Francis; Jörgen Johansson; Åke Forsberg; Luís Jaime Mota; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; type III secretion system; translocation; translocon; regulation; bacteria-eukaryotic cell contact; cytokine profiling;

   Sammanfattning : Many Gram negative bacteria use type III secretion systems to cross-talk with eukaryotic cells. Type III secretion system assembly and function is tightly regulated. LÄS MER

5. 4. Role of YopE and LcrH in effector translocation, HeLa cell cytotoxicity and virulence

   Författare :Margareta Aili; Roland Rosqvist; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; bacterial pathogenesis; YopE; LcrH; virulence; effector translocation; type III secretion; regulation; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : In order to establish an extra-cellular infection the gram-negative bacteria Yersinia pseudotuberculosis uses a type III secretion system (T3SS) to translocate a set of anti-host effectors into eukaryotic cells. The toxins disrupt signalling pathways important for phagocytosis, cytokine production and cell survival. LÄS MER