Sökning: "Yersinia"

Visar resultat 6 - 10 av 61 avhandlingar innehållade ordet Yersinia.

  1. 6. Delivery of TypeIII Secreted Toxins by Yersinia pseudotuberculosis : the Role of LcrV, YopD, and Free Lipids in the Translocation Process

    Författare :Jan Olsson; Hans Wolf-Watz; Ina Attree; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yersinia; T3SS; translocation; YopD; LcrV; YLC; fatty acids.; Molecular biology; Molekylärbiologi;

    Sammanfattning : Bacteria that infect humans and animals face a hard combat with the host´s immune system and in order to establish infection, pathogenic bacteria has evolved mechanisms to avoid being cleared from the host tissue. Many Gram-negatives carry a Type 3 secretion (T3S) system that is used to deliver effector proteins (toxins) into host cells. LÄS MER

  3. 7. Role of the Yersinia protein YopK in microbe-host interactions

    Författare :Sara Thorslund; Maria Fällman; James Bliska; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; YopK; T3SS; antiphagocytosis; neutrophil; translocation; virulence; molekylärbiologi; Molecular Biology;

    Sammanfattning : There are three human pathogenic species of the genus Yersiniae: Yersinia pestis, Yersinia enterocolitica, and Yersinia pseudotuberculosis. To cause disease, these strains inhibit several key innate defense mechanisms, including phagocytosis, the critical process for bacterial clearance. LÄS MER

  4. 8. Twin-arginine translocation in Yersinia : the substrates and their role in virulence

    Författare :Ummehan Avican; Åke Forsberg; Åsa Sjöling; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Yersinia pseudotuberculosis; Tat; virulence; Tat substrates; SufI; stress response; metabolism; infection; transcriptome analysis; Infectious Diseases; infektionssjukdomar; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Pathogenic Yersinia cause a manifold of diseases in humans ranging from mild gastroenteritis (Y. pseudotuberculosis and Y. enterocolitica) to pneumonic and bubonic plague (Y. LÄS MER

  5. 9. Meticulous control of the T3SS of Yersinia is essential for full virulence

    Författare :Ann-Catrin Björnfot; Hans Wolf-Watz; Kelly T. Hughes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yersinia; type III secretion; YscU; substrate specificity switch; heat shock proteins; VagH; methyltransferase; virulence; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The type III secretion system (T3SS) of pathogenic Yersinia pseudotuberculosis is involved in virulence. The syringe-like secretion system spans both bacterial membranes and is responsible for the ability of Yersinia to transfer toxic proteins (Yop proteins) into the eukaryotic target cell. LÄS MER

  7. 10. Multiple functions of YopN in the Yersinia pseudotuberculosis type III secretion system : from regulation to in vivo infection

    Författare :Sarp Bamyaci; Åke Forsberg; Edouard Galyov; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system; Yersinia; YopN; virulence; phagocytosis; mouse infection; secretion kinetics;

    Sammanfattning : The type 3 secretion systems (T3SSs) are virulence mechanisms used by various Gram-negative bacteria to overcome the host immunity. They are often target-cell contact induced and activated. Activation results in targeting of virulence effector substrates into host cells. LÄS MER