Sökning: "Y-chromosome"

Visar resultat 6 - 10 av 32 avhandlingar innehållade ordet Y-chromosome.

1. 6. Population Genetics of Human Genomic Elements

   Författare :Thijessen Naidoo; Mattias Jakobsson; Guillaume Achaz; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; population genetics; human genome; functional elements; natural selection; pseudogenes; loss-of-function; gene regulation; Y chromosome; Biology with Specialisation in Human Evolution and Genetics; Biologi med inriktning mot människans evolution och genetik;

   Sammanfattning : The genomes of living organisms are composed of a multitude of functional units, which interact with each other and their environment in a highly regulated fashion, to facilitate the expression of an enduring (and evolving) phenotype. Several approaches have emerged in the effort to identify these functional units and explore their activities. LÄS MER

3. 7. Consequences of the Domestication of Man’s Best Friend, The Dog

   Författare :Susanne Björnerfeldt; Carles Vilà; Elena Jazin; Daniel Bradley; Uppsala universitet; []
   Nyckelord :Molecular genetics; mitochondrial genome; Y chromosome; microsatellites; disruptive selection; breed structure; whole genome amplification; gene flow; linkage disequilibrium; Canis familiaris; Canis lupus; Genetik;

   Sammanfattning : The dog was the first animal to be domesticated and the process started at least 15 000 years ago. Today it is the most morphologically diverse mammal, with a huge variation in size and shape. LÄS MER

4. 8. Sensitive Identification Tools in Forensic DNA Analysis

   Författare :Hanna Edlund; Marie Allen; Niels Morling; Uppsala universitet; []
   Nyckelord :forensic genetics; STRs; Y-chromosome; Pyrosequencing; mitochondrial DNA; skeletal remains; DNA extraction; MEDICINE; MEDICIN; Medicinsk genetik; Medical Genetics;

   Sammanfattning : DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. LÄS MER

5. 9. Analysis of Nucleotide Variations in Non-human Primates

   Författare :Ann-Charlotte Rönn; Ann-Christine Syvänen; Mats Nilsson; Phillip Morin; Uppsala universitet; []
   Nyckelord :Molecular genetics; SNP; genotyping; primate; chimpanzee; whole genome amplification; multiple displacement amplification; minisequencing; microarray; Y-chromosome; mitochondria; Genetik;

   Sammanfattning : Many of our closest relatives, the primates, are endangered and could be extinct in a near future. To increase the knowledge of non-human primate genomes, and at the same time acquire information on our own genomic evolution, studies using high-throughput technologies are applied, which raises the demand for large amounts of high quality DNA. LÄS MER

7. 10. Conservation genomics in inbred Scandinavian wolves using bioinformatic methods

   Författare :Linnéa Smeds; Hans Ellegren; Giorgio Bertorelle; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; conservation genomics; Canis lupus; bioinformatics; Y chromosome; admixture; genetic load; structural variation; GWAS; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : With the recent and unprecedented progress in retrieving DNA sequence information from a large number of individuals of any species, conservation genetic research has entered a new phase. Specifically, it has become possible to study how genomes of endangered species respond to reductions in population size. LÄS MER