Sökning: "Xiao-qun Zhang"

Hittade 1 avhandling innehållade orden Xiao-qun Zhang.

1. 1. Functional Studies on the PDGFR α gene promoter and effects of autocrine PDGF-A stimulation in vivo

   Författare :Xiao-Qun Zhang; Hubert Schorle; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Autorcrine PDGF; promoter; PDGFRA; transgenic mice; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Platelet-derived growth factor receptor α (PDGFRα) plays an important role during embryogenesis. After implantation, the patterns of expression of Pdgfrα and its ligand Pdgf-A undergo an "autocrine-paracrine transition", in that Pdgf-A becomes expressed in the ectoderm and epithelia, while Pdgfrα is expressed in the adjacent mesenchymal tissue. LÄS MER