Sökning: "XAF1"

Hittade 2 avhandlingar innehållade ordet XAF1.

1. 1. Early oncogenic events and defective apoptosis in prostate cancer

   Författare :Xiaolei Fang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Prostate cancer; HGPIN; ezrin; pim-1; XAF1; apoptosis; DNA methylation; immunohistochemistry; FISH;

   Sammanfattning : Prostate cancer is one of the most common malignancies in males in the Western world. Although the mechanisms are unclear, it is generally believed that the accumulation of genetic alterations leads to the tumor formation. LÄS MER

3. 2. The role of KIF1Bß in neuroblastoma tumour suppression during sympathetic neuron development

   Författare :Stuart Fell; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Neuroblastoma, the most common extra-cranial childhood tumour, is believed to arise from precursor cells of the sympathetic nervous system (neuroblasts). Hemizygous loss of chromosome 1p36 strongly correlates with poor prognosis in neuroblastoma and the 1p36 gene KIF1Bβ has been proposed to be a pathogenic target of this deletion. LÄS MER