Sökning: "Wnt5a"

Visar resultat 6 - 10 av 28 avhandlingar innehållade ordet Wnt5a.

1. 6. Gene Therapy for Neurological Disorders

   Författare :Jan Tönnesen; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epileptiform activity; striatum; organotypic culture; electrophysiology; Wnt5a; synaptic connectivity.; cell transplantation; hippocampus; neural stem cells; epilepsy; functional integration; Parkinson’s disease; optogenetics; Gene therapy;

   Sammanfattning : Gene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. LÄS MER

3. 7. Immune Tolerance Mechanisms in Human Breast Cancer

   Författare :Meliha Mehmeti; Malmö Cancerimmunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Immune tolerance; Toll-like receptors; DAMP; Wnt5a; TAMP; Myeloid-derived suppressor cells; Autoimmune regulator;

   Sammanfattning : .... LÄS MER

4. 8. The role of WNT5A in oral squamous cell carcinoma

   Författare :Zdenka Prgomet; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Cancer is one of the leading causes of death worldwide and furtherresearch into the cancer biology is required to improve treatment andsurvival. Cancer can start in all sites of the body and is characterizedby uncontrolled cell growth and capability of invading surroundingtissue and spreading to other sites of the body. LÄS MER

5. 9. Regulation of WNT5A Expression in Malignant Melanoma: Role in Tumor Progression

   Författare :Farnaz Moradi; Malmö Experimentell patologi; []
   Nyckelord :Malignant Melanoma; WNT5A; RNA binding protein HuR; Interleukin 6; BRAF inhibitor resistant cells;

   Sammanfattning : .... LÄS MER

7. 10. Wnts in development : focus on midbrain

   Författare :Emma Rakel Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Studies in the field of embryonic development reveal the temporal and spatial requirement of specific genes/proteins in the formation of a given tissue. The specific knowledge of which genes/proteins regulate development of the ventral midbrain (VM) provides a guideline for the in vitro differentiation of specific cell types therein, such as dopaminergic (DA) neurons. LÄS MER