Sökning: "Wnt"

Visar resultat 6 - 10 av 149 avhandlingar innehållade ordet Wnt.

  1. 6. Early Rostrocaudal Patterning of the CNS

    Författare :Ulrika Nordström; Thomas Edlund; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CNS development; neural patterning; neural specification; Wnt; FGF; RA; Isthmic organizer; motor neurons; rostrocaudal patterning.; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The transformation of an initially uniform population of epiblast cells into an intricately complex central nervous system (CNS) is one of the most fascinating processes during embryonic development. Presumptive neural cells are initially specified as cells of forebrain character. LÄS MER

  3. 7. Specification of Dorsal and Intermediate Telencephalic Character

    Författare :Matthew Marklund; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; telencephalon; forebrain; dorsoventral patterning; WNT; FGF; RA; retinoid-mediated signaling; development; specification; cortex; striatal; intermediate; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The telencephalon is the most highly evolved region of the vertebrate central nervous system (CNS). The major structures of the telencephalon - the cortex and basal ganglia – derive from the dorsally positioned pallium and the ventrally positioned subpallium, respectively. LÄS MER

  4. 8. Analysis of signaling pathway activity in single cells using the in situ Proximity Ligation Assay

    Författare :Linda Arngården; Ola Söderberg; Niclas Karlsson; Uppsala universitet; []
    Nyckelord :cell signaling; Wnt; Hippo; TGFB; Molekylär medicin; Molecular Medicine;

    Sammanfattning : A cell that senses signals from its environment uses proteins for signal transduction via post translational modifications (PTMs) and protein- protein interactions (PPIs) from cell membrane into the nucleus where genes controlling cell proliferation, differentiation and apoptosis can be turned on or off, i.e. LÄS MER

  5. 9. FGFs and Wnts in pancreatic growth and β-cell function

    Författare :Stella Papadopoulou; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Wnt; FGF; pancreas; Notch; signal transduction; development; proliferation; progenitors; β-cells; feedback; GSIS; diabetes; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Mesenchymal-epithelial interactions are pivotal for proper pancreatic growth and development. The pancreatic progenitor cells present in the early pancreatic anlagen proliferate and eventually give rise to all pancreatic cell types. LÄS MER

  7. 10. A Muscle Perspective on the Pathophysiology of Amyotrophic Lateral Sclerosis : Differences between extraocular and limb muscles

    Författare :Vahid M. Harandi; Jingxia Liu; Fatima Pedrosa Domellöf; Per Stål; Fawzi Kadi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junctions; Extraocular muscles; Skeletal muscle; Neurotrophic factor; Wnt; Motor neuron disease; Amyotrophic lateral sclerosis; SOD1G93A mice; molekylärbiologi; Molecular Biology;

    Sammanfattning : Background: Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor neuron disease. LÄS MER