Sökning: "Wnt"
Visar resultat 16 - 20 av 149 avhandlingar innehållade ordet Wnt.
16. Early development of the olfactory placode and early rostrocaudal patterning of the caudal neural tube
Sammanfattning : The development of the nervous system is a complex process. Cell divisions, cell differentiation and signalling interactions must be tightly regulated. To comprehend the mature nervous system, we have to understand its assembly during development. LÄS MER
17. Exploring the tissue-specific nature of the Wnt cell signaling system : The complex world of cell communication and the search for the Achilles heel of cancer
Sammanfattning : The Wnt signaling pathway is a biological mechanism for cell-cell communication found across all species of the animal kingdom. This pathway plays a major role in virtually all stages of embryonic development, and it governs central aspects of stem cell biology, regeneration, and tissue homeostasis. LÄS MER
18. NOTUM and RSPO3 in Bone - WNT signaling modulators regulating the skeleton
Sammanfattning : Osteoporosis is a skeletal disease affecting millions of people worldwide, often leading to fragility fractures and a decreased quality of life. There is an unmet medical need for new anabolic, bone building, treatments. LÄS MER
19. Bone and Cartilage Regeneration: Wnt Signaling Pathway in Healing
Sammanfattning : The Wnt signaling pathway plays a central role in bone and cartilage embryonic development, processes that are recapitulated during regeneration. Imbalance in such well conserved and complex system often contributes to numerous diseases, whereas controlled modulation of the Wnt signaling activity is an attractive target e.g. LÄS MER
20. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer
Sammanfattning : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. LÄS MER