Sökning: "White blood cells"
Visar resultat 1 - 5 av 100 avhandlingar innehållade orden White blood cells.
1. Acoustofluidic preparation of whole blood components
Sammanfattning : Whole blood is rich in information about the physical state of an individual and is routinely used in a variety of clinical and research applications. In this thesis, the use of a microfluidic technique called acoustophoresis for separation of different blood components is explored. LÄS MER
2. Regulation of the ribosomal RNA transcription by c-MYC oncoprotein
Sammanfattning : The transcription factor c-Myc is a key regulator of growth and proliferation. c-Myc levels are tightly controlled and deregulated c-Myc is often associated with human cancers. In our initial studies we observed that upon inhibition of proteasomes, excess c-Myc accumulates primarily in the nucleoli. LÄS MER
3. Inflammatory Response in Peripheral Arterial Disease
Sammanfattning : Peripheral arterial disease (PAD) is the manifestation of atherosclerotic lesions in arteries supplying blood to the legs. Atherosclerosis is now recognized as an inflammatory disease of the vessel wall and important features in the pathophysiology are activation of WBC, endothelial cells and increased levels of inflammatory mediators. LÄS MER
4. Biomarkers in sepsis and other severe infections
Sammanfattning : Infectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. LÄS MER
5. Human truncated thioredoxin (Trx80) as a novel mitogenic cytokine for white blood cells
Sammanfattning : Thioredoxin (Trx) is a 12 kDa protein present in all species with a well-conserved active site sequence comprising -Cys-Gly-Pro-Cys-, which catalyzes oxido-reductase reactions. Trx regulates the activity of transcription factors and intracellular signalling pathways, and secreted Trx is a co-cytokine with several interleukins. LÄS MER