Sökning: "Wesley"
Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Wesley.
1. Lifestyle matters : epidemiological studies of oily fish, BMI, life events, physical workload and rheumatoid arthritis
Sammanfattning : Rheumatoid arthritis (RA), divided in two major subsets defined by presence or absence of anti-citrullinated protein antibodies (ACPA), is chronic inflammatory disease which lead to joint damage and bone destruction. It is a complex disease where both genetic and environmental factors contribute to its development. LÄS MER
2. Computational Studies of HIV-1 Protease Inhibitors
Sammanfattning : Human Immunodeficiency Virus (HIV) is the causative agent of the pandemic disease Acquired Immune Deficiency Syndrome (AIDS). HIV acts to disrupt the immune system which makes the body susceptible to opportunistic infections. Untreated, AIDS is generally fatal. LÄS MER
3. Confidence Predictions in Pharmaceutical Sciences
Sammanfattning : The main focus of this thesis has been on Quantitative Structure Activity Relationship (QSAR) modeling using methods producing valid measures of uncertainty. The goal of QSAR is to prospectively predict the outcome from assays, such as ADMET (Absorption, Distribution, Metabolism, Excretion), toxicity and on- and off-target interactions, for novel compounds. LÄS MER
4. Assessing inbreeding and loss of genetic variation in canids, domestic dog (Canis familiaris) and wolf (Canis lupus), using pedigree data
Sammanfattning : Genetic variation is necessary to maintain the ability of wild and domestic populations to genetically adapt to changed selective pressures. When relationships among individuals are known, conservation genetic management can be based on statistical pedigree analysis. LÄS MER
5. The “Dark Side” of Marine Spatial Planning : A study of domination, empowerment and freedom through theories of discourse and power
Sammanfattning : This thesis aims to contribute to the marine spatial planning (MSP) literature by elaborating a robust theoretical account of power for a more rigorous and balanced critical analysis of MSP. Conceived as a problem-solving regime, MSP has emerged as a radical approach to govern the use and protection of marine resources. LÄS MER