Sökning: "WNT"

Visar resultat 1 - 5 av 149 avhandlingar innehållade ordet WNT.

1. 1. Role of Wnt-5a in breast cancer

   Författare :Janna Sand-Dejmek; Malmö Experimentell patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; signal transduction; metastasis; adhesion; breast cancer; Syk; Wnt-5a; DDR1; pathological anatomy; Patologi allmän ; patologisk anatomi;

   Sammanfattning : Breast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. LÄS MER

3. 2. Wnt-5a signaling in breast cancer metastasis

   Författare :Annette Säfholm; Malmö Experimentell patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; patologisk anatomi; General pathology; cancer; onkologi; Cytologi; breast cancer; Wnt-5a; migration; pathological anatomy; metastasis; signal transduction; peptides; Cytology; cancerology; oncology;

   Sammanfattning : Breast cancer is the most common form of malignancy affecting women in the Western world. Today, anticancer treatment can control primary breast tumors, but treatment and prevention of metastatic disease still represents a major challenge in the management of breast cancer patients. LÄS MER

4. 3. Molecular characterization of FOX factors and Wnt signalling interplay in human cancers

   Författare :Giulia Pizzolato; Stefan Koch; Åsa Keita; Boudewijn Burgering; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FOX proteins; Wnt signalling; p53; Tumour biology; Transcription factors; Proteine FOX; Via di segnalazione Wnt; p53; Biologia dei tumori; Fattori di trascrizione;

   Sammanfattning : Wnt/β-catenin signalling, also referred to as canonical Wnt signalling, is a critical regulator of tissue homeostasis and of the differentiation of cells during development. The outcome of canonical Wnt pathway activity is defined by the regulation of target gene transcription, which ultimately determines cell identity and proliferation. LÄS MER

5. 4. Effects of cytokines on preadipocyte differentiation and Wnt signalling

   Författare :Birgit Gustafson; Göteborgs universitet; []
   Nyckelord :adipocyte differentiation; adiponectin; beta-Catenin; C EBPalpha; IL-6; PPARgamma; TNFalpha; Wnt signalling;

   Sammanfattning : The relationship between amount of adipose tissue, the Metabolic Syndrome and Type 2 diabetes has been recognized for several years. However, the mechanisms for this remain to be clarified. Not all obese individuals develop insulin resistance or Type 2 diabetes and these perturbations are also seen in non-obese individuals. LÄS MER

7. 5. Analysis of Wnt ligands and Fz receptors in Ecdysozoa : Investigating the evolution of segmentation

   Författare :Mattias Hogvall; Ralf Janssen; Graham Budd; Andreas Hejnol; Javier Ortega-Hernández; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Segmentation; Onychophora; Wnt genes; Frizzled; Hox genes; Priapulida; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

   Sammanfattning : .... LÄS MER