Sökning: "Voltage-gated Ca2 Channels"
Visar resultat 6 - 10 av 33 avhandlingar innehållade orden Voltage-gated Ca2 Channels.
6. The Best Leading Role for Maintaining Normal β-cell Function Goes to MafA and Voltage-gated Calcium Channel Subunit γ4
Sammanfattning : .... LÄS MER
7. Roles of the transient receptor potential channels and the intracellular Ca2+ channels in Ca2+ signaling in the beta-cells
Sammanfattning : Previous studies from our group reported that pancreatic β-cells express ryanodine receptors (RyRs) that can mediate Ca2+-induced Ca2+ release (CICR). The full consequences of the activation of RyRs on Ca2+ signaling in these cells, however, remained unclear. LÄS MER
8. Architecture and function of the insulin granule secretion machinery
Sammanfattning : Insulin is released into the blood stream to normalize elevated blood glucose, for example after a meal. The hormone is synthesized by β-cells in the endocrine pancreas, and stored in small vesicles, known as secretory granules, until required. When glucose is elevated, these granules undergo regulated exocytosis and thereby secrete the hormone. LÄS MER
9. Dendritic and axonal ion channels supporting neuronal integration : From pyramidal neurons to peripheral nociceptors
Sammanfattning : The nervous system, including the brain, is a complex network with billions of complex neurons. Ion channels mediate the electrical signals that neurons use to integrate input and produce appropriate output, and could thus be thought of as key instruments in the neuronal orchestra. LÄS MER
10. Role of potassium channels in regulating neuronal activity
Sammanfattning : The firing behaviour of excitable cells is fundamental for the information processing in multicellular organisms, varying from single spikes to different forms of repetitive firing. Of the many regulators, voltage gated potassium channels play a major role. In this thesis some aspects of the potassium channel regulation of firing are explored. LÄS MER