Sökning: "Vladimir Tolmachev"

Visar resultat 21 - 22 av 22 avhandlingar innehållade orden Vladimir Tolmachev.

  1. 21. Molecular Imaging of HER2 Expression using Synthetic Affibody Molecules : Design, Synthesis and Biological Evaluation

    Författare :Thuy Tran; Vladimir Tolmachev; Uwe Haberkorn; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : Molecular imaging is an emerging multidisciplinary field that addresses the visualisation of diseases at the cellular and molecular levels. This thesis focuses on the development of a synthetic Affibody molecule-based imaging tracer for the detection of HER2 expression in malignant tumours. LÄS MER

  3. 22. Targeting Biological Systems by Organic Synthesis Methods - Cancer Cells and Proteins

    Författare :Cecilia Winander; Lars Baltzer; Stefan Sjöberg; Jörgen Carlsson; Vladimir Tolmachev; Thomas Schrader; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; carborane; doxorubicin; 125I; molecular recognition; four-helix bundle; polypeptide conjugate; affinity; chitinase; acetylcholine esterase; Organisk kemi;

    Sammanfattning : This thesis describes the design and synthesis of molecules with potential roles in biomedicine, with an emphasis on molecular recognition in complex biological environments. The first chapter describes the synthesis and evaluation of compounds for use in nuclide therapy. LÄS MER