Sökning: "Virus Activation"

Visar resultat 21 - 25 av 252 avhandlingar innehållade orden Virus Activation.

  1. 21. Activation of the spike proteins of alpha- and retroviruses

    Författare :Shang-Rung Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alphavirus; Retrovirus; Fusion protein; electron cryomicroscopy; intermediate structure;

    Sammanfattning : Enveloped viruses like human immunodeficiency virus type 1 (HIV-1) enter cells by fusing their membrane with that of the cell plasma membrane, while others, like influenzavirus and alphavirus enter via uptake into endosomes and fusion with the endosomal membrane. For this they carry spike proteins. LÄS MER

  3. 22. Epstein-Barr virus gene methylation and variation in latency

    Författare :Kerstin I Falk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epstein-Barr virus is a human herpesvirus and approximately 95 % of the adults carry the virus in a latent form. EBV has been implicated in the pathogenesis of human malignancies such as Burkitt's lymphoma and nasopharyngeal carcinoma. DNA methylation is one of the mechanisms that is involved in control of gene expression in viruses. LÄS MER

  4. 23. Epstein-Barr virus (EBV) latent membrane protein (LMP) 2A

    Författare :Fu Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epstein-Barr virus (EBV) is a ubiquitous human herpes virus which infects more than 90% of individuals in the population and is causally implicated in lymphoid and epithelial malignancies. Virus invades oropharyngeal mucosa and establishes latency in memory B lymphocytes. LÄS MER

  5. 24. Molecular characterization of the hepatitis C virus core protein

    Författare :Priya Devi; Anders Bergqvist; Björn Olsen; Tanel Punga; Gerald McInerney; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; HCV; core protein; SHP-1; CpG methylation; bisulfite sequencing; NGS; PBMC; Ca2 NFAT; strand-specific RT qPCR; Klinisk virologi; Clinical Virology; Infektionssjukdomar; Infectious Diseases; Mikrobiologi; Microbiology; Medical Virology; Medicinsk virologi;

    Sammanfattning : Hepatitis C virus (HCV) is an RNA virus that causes chronic infection, which can lead to hepatocellular carcinomas in humans. Besides liver diseases, the chronic HCV infection causes a broad spectrum of extrahepatic complications such as lymphoproliferative, metabolic and autoimmune disorders. LÄS MER

  7. 25. Complement activation - good or evil in HIV-1 infection? : interaction of free and complement opsonized HIV-1 with monocyte derived dendritic cells and immune cells in the cervical mucosa

    Författare :Veronica Tjomsland; Marie Larsson; Jorma Hinkula; Karl-Eric Magnusson; Barbara Shacklett; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Worldwide, the heterosexual route is the most common mode of sexual transmission of HIV-1 and women are particularly susceptible to this infection. After penetration of the mucosal epithelium HIV-1 interacts with potential target cells, i.e. dendritic cells (DCs) and CD4+ T cells. LÄS MER