Sökning: "Virtual replacement"

Hittade 5 avhandlingar innehållade orden Virtual replacement.

1. 1. Computational Methods in Medicinal Chemistry : Mechanistic Investigations and Virtual Screening Development

   Författare :Fredrik Svensson; Christian Sköld; Anders Karlén; Anna Linusson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DFT; IRAP; Virtual Screening; Catalysis; Palladium; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : Computational methods have become an integral part of drug development and can help bring new and better drugs to the market faster. The process of predicting the biological activity of large compound collections is known as virtual screening, and has been instrumental in the development of several drugs today in the market. LÄS MER

3. 2. The Origin of Tooth Replacement : Three-dimensional Synchrotron Histology Visualizes the Dental Development of Silurian Stem Osteichthyans

   Författare :Donglei Chen; Per Ahlberg; Zerina Johanson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Mechanisms of tooth replacement distribute incongruently among extant gnathostomes (jawed vertebrates): a permanent tooth-generating dental lamina exists in chondrichthyans (cartilaginous fish) and tetrapods but not teleosts, whereas tooth shedding by basal hard tissue resorption occurs in tetrapods and teleosts but not chondrichthyans. Theories about the evolution of tooth development have been biased towards the chondrichthyan conveyor-belt replacement, since there has been no fossil evidence for the origin of osteichthyan (bony fish and tetrapods) tooth replacement until now. LÄS MER

4. 3. Cost optimization of maintenance scheduling for wind turbines with aging components

   Författare :Quanjiang Yu; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Integer linear optimization; Age-based preventive maintenance scheduling; Renewal-reward theorem; Weibull distribution; Combinatorial optimization; Wind turbine maintenance; Virtual replacement; Condition monitoring data; Cox proportional hazards method; Linear programming;

   Sammanfattning : A major part of the wind turbine operation cost is resulted from the maintenance of its components. This thesis deals with the theory, algorithms, and applications concerning minimization of the maintenance cost of wind power turbines, using mathematical modelling to find the optimal schedules of preventive maintenance activities for multi-component systems. LÄS MER

5. 4. Biocomputational studies on protein structures

   Författare :Erik Nordling; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Biology in the post-genomic era produces large amount of data. This, in combination with the need for efficient algorithms to find genes in the genomic material, has brought a renaissance into the field of computational biology. LÄS MER

7. 5. Selected Applications of Switched Capacitor Circuits : RF N-Path Filters and ΣΔ Modulators

   Författare :Fahad Qazi; Jerzy Dabrowski; Atila Alvandpour; Henrik Sjöland; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : Electronic circuits based on switches and capacitors have been used in various applications for several decades. The common switched capacitor (SC) circuits have made their career primarily in analog filters and data converters due to high immunity to capacitance mismatch in integrated circuit (IC) technologies. LÄS MER