Sökning: "Vinícius Motta"

Hittade 1 avhandling innehållade orden Vinícius Motta.

1. 1. The genetic basis of T and B cell contribution to autoimmune diabetes in NOD mice

   Författare :Vinícius Motta; Dan Holmberg; Linda Wicker; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; CTLA-4; superantigen; T cells; Idd; marginal zone B cells; embryo aggregation chimera; negative selection; Immunogenetics; Immungenetik;

   Sammanfattning : The nonobese diabetic mouse (NOD) is an excellent animal model to study type 1 diabetes. As with some humans, disease in the NOD mouse is effected by a combination of genetic and environmental factors. At least 20 insulin dependent diabetes (Idd) susceptibility loci have been identified so far, both in humans and in the NOD mouse. LÄS MER