Sökning: "Vibrio cholerae O1"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Vibrio cholerae O1.

1. 1. Modulators of Vibrio cholerae predator interaction and virulence

   Författare :Barbro Lindmark; Sun Nyunt Wai; Kristian Riesbeck; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; Caenorhabditis elegans; PrtV; outer membrane vesicles; non-O1 non-O139; serum resistance; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : Vibrio cholerae, the causal agent of cholera typically encodes two critical virulence factors: cholera toxin (CT), which is primarily responsible for the diarrhoeal purge, and toxin-co-regulated pilus (TCP), an essential colonisation factor. Nontoxigenic strains expressing TCP can efficiently acquire the CT gene through lysogenic conversion with CTXΦ, a filamentous phage that encodes CT and uses TCP as a receptor. LÄS MER

3. 2. Effect of virulence factors on survival strategies of vibrio cholerae and vibrio mimicus

   Författare :Soni Priya Valeru; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Vibrio cholerae;

   Sammanfattning : Vibrio is a genus of gram-negative bacteria comprising nearly 70 species and they are clinically human pathogens that can cause many infections. This study is mainly based on two species such as Vibrio cholerae O1 El Tor, which cause cholera disease and Vibrio mimicus, that cause gastroenteritis, open wounds infection, and septicemia. LÄS MER

4. 3. Development of novel vaccine strains of Vibrio cholerae and studies on the role of serotype in epidemic spread of cholera

   Författare :Stefan Karlsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera; Vibrio cholerae; Serotype; Ogawa; Inaba; Hikojima; Vaccine; Immunogenicity; serotype switching; wbeT;

   Sammanfattning : Cholera, caused by bacterium Vibrio cholerae O1, is a severe diarrheal disease with an estimated 3-5 million cases and more than 140 000 deaths every year particularly affecting children under 5 years of age. It can be found all over the world and often causes cholera in places where access to clean water or proper sanitary facilities are limited or compromised. LÄS MER

5. 4. A mouse model for direct evaluation of cholera vaccines

   Författare :Erik Nygren; Göteborgs universitet; []
   Nyckelord :Vibrio cholerae; cholera vaccine; cholera toxin; LPS; anti-bacterial immunity; IgA; challenge; protection; colonization;

   Sammanfattning : Cholera continues to be an important cause of morbidity and mortality in large parts of the developing world and is a significant negative factor for economic development. Vibrio cholerae bacteria of the O1 or O139 serogroup can cause disease due to their ability to colonize the intestine and produce an enterotoxin, cholera toxin (CT). LÄS MER

7. 5. Outer membrane vesicle-mediated export of virulence factors from Gram-negative bacteria

   Författare :Pramod Kumar Rompikuntal; Sun Nyunt Wai; Ann-Beth Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Outer membrane vesicles; CDT; PGN; PrtV; Campylobacter jejuni; Vibrio cholerae; Aggregatibacter actinomycetemcomitans; molekylärbiologi; Molecular Biology;

   Sammanfattning : The Gram-negative, motile bacterium Campylobacter jejuni is a causative agent of food-borne gastroenteritis. Cytolethal distending toxin (CDT) is one of the important virulence factors for C. jejuni pathogenesis. It was not previously known how CDT is released from C. LÄS MER