Sökning: "Veronica Åberg"

Hittade 1 avhandling innehållade orden Veronica Åberg.

1. 1. Peptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification of Aβ-peptide aggregation inhibitors

   Författare :Veronica Åberg; Fredrik Almqvist; Jan Kihlberg; Morten Grötli; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2-pyridone; peptidomimetic; antibacterial; pili; Escherichia coli; virulence; amyloid; Alzheimer’s.; Organic chemistry; Organisk kemi;

   Sammanfattning : This thesis describes the synthesis and biological evaluation of highly substituted, ring-fused 2-pyridones. The utility of the bicyclic 2-pyridones to gain fundamental insights into the disease processes of bacterial infections and Alzheimer’s disease has been investigated. LÄS MER