Sökning: "Vascular"

Visar resultat 11 - 15 av 1477 avhandlingar innehållade ordet Vascular.

1. 11. Angiotensin II and vascular disease. Studies in rats and atherosclerosis-prone mice

   Författare :Maria E Johansson; Göteborgs universitet; []
   Nyckelord :angiotensin II; atherosclerosis; AT1 receptor; AT2 receptor; blood pressure; hyperinsulinemia; hypertension; oxidative stress; salt; vascular disease; vascular function;

   Sammanfattning : Angiotensin II (Ang II) is of importance for a number of physiological processes but also plays an important pathophysiological role in cardiovascular disease. The aim of this thesis was to evaluate the role of Ang II in hypertension-related atherosclerosis and vascular disease and to investigate possible anti-atherosclerotic effects of the angiotensin II, type 2 (AT2) receptor. LÄS MER

3. 12. Vascular actions of antimicrobial peptides

   Författare :Cristina Ciornei; Sektion II; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; vascular smooth muscle; sepsis; nitric oxide; human antimicrobial peptide LL-37; Antimicrobial peptides; lipopolysaccharide; bactericidal permeability-increasing protein;

   Sammanfattning : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). LÄS MER

4. 13. Transcriptional and post-transcriptional regulation of vascular smooth muscle cell phenotype - Implications for vascular disease states

   Författare :Azra Alajbegovic; Molekylär kärlfysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Vascular smooth muscle cells VSMC ; cell phenotype; microRNA; Aneurysm; hypertension; Actin polymerization; GATA6; MRTFA; Vascular disease;

   Sammanfattning : As the world population is pushing toward 8 billion, cardiovascular diseases (CVD) remain the leading cause of death worldwide, representing 30% of all global deaths. A large body of work has recognized that smooth muscle cells (SMCs) surrounding the blood vessels play a prominent role in the development and progression of cardiovascular diseases. LÄS MER

5. 14. Perlecan in vascular disease

   Författare :Tran Phan Kiet; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Perlecan; heparan sulfate; smooth muscle cells; intimal hyperplasia; vascular disease; atherosclerosis; restenosis; heparin-binding growth factor.;

   Sammanfattning : Atherosclerosis has become the most common cause of death in the world. The development of the disease involves accumulation of lipids in the inner layer of the vessel wall, the intima, and recruitment of inflammatory cells and smooth muscle cells (SMCs). LÄS MER

7. 15. Thrombolysis in vascular surgery

   Författare :Linn Smith; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background and aims: Thrombolysis is in common use in the treatment of acute forms of vascular disease. It may be used both systemically and locally, in the latter case through an endovascular approach, socalled catheter-directed thrombolysis. LÄS MER