Sökning: "Vascular stiffness"

Visar resultat 1 - 5 av 47 avhandlingar innehållade orden Vascular stiffness.

  1. 1. Epidemiological, mechanistic and genetic aspects of vascular ageing and arterial stiffness in the population

    Författare :Mikael Gottsäter; Internmedicin - epidemiologi; []
    Nyckelord :Vascular ageing; Arterial stiffness;

    Sammanfattning : The core feature of vascular ageing is the age-associated stiffening of the large, elastic arteries, or arteriosclerosis. This results in a diminished volume-buffering function and is therefore central for the increase in systolic blood pressure and pulse pressure seen with advancing age. LÄS MER

  2. 2. Biomarkers of vascular function and structure in young healthy adults

    Författare :Paul Pettersson-Pablo; Anita Hurtig-Wennlöf; Torbjörn Nilsson; Lars Breimer; Anders Larsson; Örebro universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; vascular function; vascular structure; body composition; age; inflammation; clinical chemistry; biomarker;

    Sammanfattning : Atherosclerosis is a disease affecting the blood vessels in the body. Its pathophysiologic mechanisms involve infiltration of the vessel walls by fatty matter and immune cells. This process is slow, starting in childhood but typically not manifesting as symptomatic disease until late adulthood (after 60 years of age). LÄS MER

  3. 3. Effects of physical exercise on coronary and peripheral vascular function. An integrative physiological study from rat to man

    Författare :Ulrika Hägg Samuelsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :exercise; endothelial function; coronary flow velocity reserve; colour Doppler echocardiography; oxidative stress; gene expression; stiffness; ultrasound biomicroscopy;

    Sammanfattning : Physical exercise is beneficial for the cardiovascular health. Numerous epidemiological studies reveal that physical activity reduces the risk of cardiovascular related death. Nevertheless, the underlying vessel wall specific physiological and molecular mechanisms still remain incompletely understood. LÄS MER

  4. 4. Stiffness and aneurysm of the aorta. Relations to vascular aging, hyperglycemia, and inflammation

    Författare :Soumia Taimour; Vaskulära sjukdomar - kliniska studier; []

    Sammanfattning : A well-functioning arterial system for the transport of oxygen to the cells is essential for human health. The aorta has a key role for the provision of this physiological effect. Disturbances to aortic function can lead to majorsymptoms and even death due to ruptured abdominal aortic aneurysm (AAA). LÄS MER

  5. 5. Systemic sclerosis : vascular, pulmonary and immunological aspects

    Författare :Grethe Neumann Andersen; Solbritt Rantapää Dahlqvist; Lucia Mincheva-Nilsson; Sören Jacobsen; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; interstitial lung disease; MMP-9; Th1 Th2; transcription factors; NO; iNOS; E-selectin; endothelium-dependent dilation; endothelium-independent dilation.; Rheumatology; Reumatologi;

    Sammanfattning : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality. The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. LÄS MER